Term Name: |
midafotel |
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Search Ontology:
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Synonyms: |
- (2R)-4-[(2E)-3-phosphono-2-propenyl]-2-piperazinecarboxylic acid
- (2R)-4-[(2E)-3-phosphonoprop-2-en-1-yl]piperazine-2-carboxylic acid
- (R)-4-[(E)-3-phosphonoprop-2-enyl]piperazine-2-carboxylic acid
- (R)-CPP-ene
- D(-)CPPene
- D-4-[(2E)-3-phosphono-2-propenyl]-2-piperazinecarboxylic acid
- D-CPP-ene
- D-CPPene
- midafotel
- midafotelum
- SDZ EAA 494
- SDZ-EAA 494
- SDZ-EAA-494
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Definition: |
A member of the class of piperazines that is piperazine substituted by a carboxy group at position 2R and a (1E)-1-phosphonoprop-1-en-3-yl group at position 4. It is an antagonist of N-methyl-D-aspartate receptors (NMDARs) and was in clinical development by Novartis for the treatment of cognition disorders and brain injuries (now discontinued).
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References: |
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Ontology: |
ChEBI
(
EBI
)
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