OBO ID: CHEBI:173104

Term Name:	narlaprevir		Search Ontology:
Synonyms:	(1R,2S,5S)-3-[N-({1-[(tert-butylsulfonyl)methyl]cyclohexyl}carbamoyl)-3-methyl-L-valyl]-N-[(3S)-1-(cyclopropylamino)-1,2-dioxoheptan-3-yl]-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxamide (1R,2S,5S)-3-{(2S)-2-[({1-[(tert-butylsulfonyl)methyl]cyclohexyl}carbamoyl)amino]-3,3-dimethylbutanoyl}-N-[(3S)-1-(cyclopropylamino)-1,2-dioxoheptan-3-yl]-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxamide (1R,2S,5S)-N-[(3S)-1-(cyclopropylamino)-1,2-dioxoheptan-3-yl]-6,6-dimethyl-3-[3-methyl-N-({1-[(2-methylpropane-2-sulfonyl)methyl]cyclohexyl}carbamoyl)-L-valyl]-3-azabicyclo[3.1.0]hexane-2-carboxamide Arlansa narlaprevir narlaprevirum SCH 900518 SCH-900518 SCH900518
Definition:	An azabicyclohexane that is (1R,5S)-6,6-dimethyl-3-azabicyclo[3.1.0]hexane substituted by [(3S)-1-(cyclopropylamino)-1,2-dioxoheptan-3-yl]aminoacyl and N-({1-[(tert-butylsulfonyl)methyl]cyclohexyl}carbamoyl)-3-methyl-L-valyl groups at positions 2S and 3, respectively. It is a hepatitis C virus (HCV) NS3/4A serine protease inhibitor (Ki = 6 nM) that is used for the treatment of chronic hepatitis C.
References:	CAS:865466-24-6 Chemspider:10031710 DrugBank:DB14760 KEGG:D09644 LINCS:LSM-45473 PDBeChem:NNA PMID:20308381 PMID:20938912 PMID:21473061 PMID:21627104 PMID:22263860 PMID:23490393 PMID:24168257 PMID:24900178 PMID:25178998 PMID:27645244 PMID:32598756 PMID:33152262 PMID:33524017 PMID:33538596 PMID:33542181 Wikipedia:Narlaprevir
Ontology:	ChEBI  ( EBI )