OBO ID: CHEBI:167308
Term Name: dextromethadone Search Ontology:
Synonyms:
  • (+)-(S)-6-(dimethylamino)-4,4-diphenyl-3-heptanone
  • (+)-methadone
  • (6S)-6-(dimethylamino)-4,4-diphenylheptan-3-one
  • (6S)-methadone
  • (S)-(+)-methadone
  • (S)-6-(dimethylamino)-4,4-diphenyl-3-heptanone
  • (S)-methadone
  • d-6-(dimethylamino)-4,4-diphenyl-3-heptanone
  • d-methadone
  • REL-1017
  • S-(+)-methadone
  • S-methadone
Definition: A 6-(dimethylamino)-4,4-diphenylheptan-3-one that has (S)-configuration. It is the less active enantiomer of methadone and has very little activity on opioid receptors and mainly responsible for the inhibition of hERG K+ channels and thus for cardiac toxicity. The drug is currently under clinical development for the treatment of major depressive disorder.
References:
Ontology: ChEBI  ( EBI )
Relationships
is a type of:
has_role:
inverse has_part:
inverse is_enantiomer_of:
is_enantiomer_of:
PHENOTYPE No data available

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