OBO ID: CHEBI:167004
Term Name: fostriecin Search Ontology:
Synonyms:
  • (+)-fostriecin
  • (1E,3R,4R,6R,7Z,9Z,11E)-3,6,13-trihydroxy-3-methyl-1-[(2R)-6-oxo-3,6-dihydro-2H-pyran-2-yl]trideca-1,7,9,11-tetraen-4-yl dihydrogen phosphate
  • (6R)-5,6-dihydro-6-[(1E,3R,4R,6R,7Z,9Z,11E)-3,6,13-trihydroxy-3-methyl-4-(phosphonooxy)-1,7,9,11-tridecatetraenyl]-2H-pyran-2-one
  • antibiotic CI 920
  • antibiotic CL 1565A
  • CI 920
  • CI-920
  • CL 1565A
  • CL-1565A
  • fostriecin
  • fostriecina
  • fostriecine
  • fostriecinum
  • PD 110,161
  • PD 110161
  • PD-110,161
  • phosphotrienin
Definition: A structurally unique, naturally-occurring phosphate monoester isolated from the soil bacterium Streptomyces pulveraceus. It inhibits DNA topoisomerase II as well as several protein phosphatase including PP2A and PPA4, and exhibits potent antitumor activity against several cancer cell lines.
References:
Ontology: Chebi
PHENOTYPE No data available