ZFIN ChEBI: luteolin

OBO ID: CHEBI:15864

Term Name:	luteolin		Search Ontology:
Synonyms:	2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4-benzopyrone 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4H-1-benzopyran-4-one 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4H-chromen-4-one 3',4',5,7-Tetrahydroxyflavone 5,7,3',4'-Tetrahydroxyflavone digitoflavone flacitran Luteolin Luteolol Salifazide
Definition:	A tetrahydroxyflavone in which the four hydroxy groups are located at positions 3', 4', 5 and 7. It is thought to play an important role in the human body as an antioxidant, a free radical scavenger, an anti-inflammatory agent and an immune system modulator as well as being active against several cancers.
References:	CAS:491-70-3 Chemspider:4444102 DrugBank:DB15584 FooDB:FDB013255 HMDB:HMDB0005800 KEGG:C01514 KNApSAcK:C00000674 LINCS:LSM-5229 LIPID_MAPS_instance:LMPK12110006 MetaCyc:5734-TETRAHYDROXYFLAVONE PDBeChem:LU2 PMID:11478688 PMID:11897650 PMID:14574115 PMID:18720166 PMID:18946424 PMID:18991571 PMID:19263826 PMID:19509250 PMID:19854181 PMID:21899269 PMID:22391103 PMID:22749133 PMID:22794353 PMID:22842046 PMID:23035972 PMID:23229294 PMID:23574272 PMID:26020516 PMID:26322379 PMID:27595800 PMID:27764981 PMID:27853236 PMID:27878246 PMID:27879665 PMID:27886116 PMID:27919958 PMID:27927066 PMID:27959422 PMID:28004344 PMID:28029146 PMID:28031430 PMID:28035396 PMID:28067377 PMID:28069121 PMID:28071803 PMID:28090531 PMID:28096694 PMID:28101184 PMID:28101223 PMID:28110189 PMID:28111945 PMID:28112209 PMID:28113103 PMID:28166217 PMID:29423013 PMID:30624931 PMID:32883638 Reaxys:292084 Wikipedia:Luteolin
Ontology:	ChEBI ( EBI )

Relationships

is a type of:	3'-hydroxyflavonoid tetrahydroxyflavone 3'-hydroxyflavonoid tetrahydroxyflavone Show first 5 Terms
has_role:	angiogenesis inhibitor anti-inflammatory agent antineoplastic agent apoptosis inducer c-Jun N-terminal kinase inhibitor ... Show All 11 Terms angiogenesis inhibitor anti-inflammatory agent antineoplastic agent apoptosis inducer c-Jun N-terminal kinase inhibitor EC 2.3.1.85 (fatty acid synthase) inhibitor immunomodulator nephroprotective agent plant metabolite radical scavenger vascular endothelial growth factor receptor antagonist Show first 5 Terms
inverse has_functional_parent:	4',5,7-trihydroxy-3'-methoxyflavone 5,3'-di-O-methylluteolin 6-C-[2'-O-alpha-L-rhamnopyranosyl-(1''->2')]-alpha-L-arabinopyranosylluteolin 6-C-[2-O-alpha-L-rhamnopyranosyl-(1''->2')]-beta-D-xylopyranosylluteolin 6-C-alpha-L-arabinopyranosyl-8-C-beta-D-glucosylluteolin ... Show All 25 Terms 4',5,7-trihydroxy-3'-methoxyflavone 5,3'-di-O-methylluteolin 6-C-[2'-O-alpha-L-rhamnopyranosyl-(1''->2')]-alpha-L-arabinopyranosylluteolin 6-C-[2-O-alpha-L-rhamnopyranosyl-(1''->2')]-beta-D-xylopyranosylluteolin 6-C-alpha-L-arabinopyranosyl-8-C-beta-D-glucosylluteolin 6-hydroxyluteolin 6-hydroxyluteolin 7-O-laminaribioside 6-methoxyluteolin 7-alpha-L-rhamnoside 7-O-[beta-D-arabinopyranosyl-(1->6)-beta-D-glucosyl]luteolin carlinoside cassiaoccidentalin B diosmetin hypolaetin isoorientin lucenin-2 luteolin 6-C-[beta-D-glucosyl-(1->2)-alpha-L-arabinoside] luteolin 7-O-(6-O-malonyl-beta-D-glucoside) luteolin 7-O-beta-D-glucoside luteolin 7-O-neohesperidoside luteolin O-glucuronoside luteolin-4'-O-beta-D-glucopyranoside luteolin-7-O-alpha-L-rhamnoside maysin ochnaflavone orientin Show first 5 Terms
inverse is_conjugate_base_of:	luteolin-7-olate luteolin-7-olate Show first 5 Terms
is_conjugate_acid_of:	luteolin-7-olate luteolin-7-olate Show first 5 Terms

PHENOTYPE No data available