Term Name: |
Glu-Gly-Arg-chloromethylketone |
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Search Ontology:
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Synonyms: |
- chloromethylketone-EGR
- EGR-chloromethylketone
- EGR-CMK
- EGRCK
- Glu-Gly-Arg-chloromethylketone
- glutamyl-glycyl-arginine chloromethyl ketone
- H-Glu-Gly-Arg-CH2Cl
- H-Glu-Gly-Arg-chloromethylketone
- L-alpha-glutamyl-N-[(3S)-6-carbamimidamido-1-chloro-2-oxohexan-3-yl]glycinamide
- L-Glu-Gly-L-Arg-chloromethylketone
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Definition: |
A tripeptide composed of L-glutamic acid, glycine and L-arginine joined in sequence by peptide linkages and in which the carboxy terminus is substituted by a chloroacetyl group. It is a potent and irreversible inhibitor of urokinase-type plasminogen activator (uPA) and factor Xa.
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References: |
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Ontology: |
ChEBI
(
EBI
)
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