OBO ID: CHEBI:156451
Term Name: holomycin Search Ontology:
Synonyms:
  • 6-(acetylamino)-1,2-dithiolo[4,3-b]pyrrol-5(4H)-one
  • 6-acetamido-1,2-dithiolo[4,3-b]pyrrol-5(4H)-one
  • N-(4,5-dihydro-5-oxo-1,2-dithiolo-[4,3-b]pyrrol-6-yl)acetamide
  • N-(5-oxo-4,5-dihydro[1,2]dithiolo[4,3-b]pyrrol-6-yl)acetamide
  • N-(5-oxo-4H-dithiolo[4,3-b]pyrrol-6-yl)acetamide
  • N-demethylthiolutin
  • N-{5-oxo-4H,5H-[1,2]dithiolo[4,3-b]pyrrol-6-yl}acetamide
Definition: A dithiolopyrrolone antibiotic that is 4,5-dihydro[1,2]dithiolo[4,3-b]pyrrole in which the hydrogens at positions 5 and 6 have been replaced by oxo and acetamido groups, respectively. It is an inhibitor of DNA-dependent RNA polymerase, and exhibits antibacterial and antitumour properties.
References:
Ontology: Chebi
PHENOTYPE No data available