OBO ID: CHEBI:156450
Term Name: thiolutin Search Ontology:
Synonyms:
  • 6-acetamido-4-methyl-1,2-dithiolo[4,3-b]pyrrol-5(4H)-one
  • acetopyrrothin
  • acetopyrrothine
  • N-(4,5-dihydro-4-methyl-5-oxo-1,2-dithiolo[4,3-b]pyrrol-6-yl)acetamide
  • N-(4-methyl-5-oxo-4,5-dihydro[1,2]dithiolo[4,3-b]pyrrol-6-yl)acetamide
  • N-(4-methyl-5-oxodithiolo[4,3-b]pyrrol-6-yl)acetamide
Definition: A dithiolopyrrolone antibiotic that is 4,5-dihydro[1,2]dithiolo[4,3-b]pyrrole in which the hydrogens at positions 4,5 and 6 have been replaced by methyl, oxo and acetamido groups, respectively. It is a potent inhibitor of RNA polymerases, inhibits the angiogenesis of human umbilical vein endothelial cells, and also inhibits JAMM metalloproteases.
References:
Ontology: Chebi
PHENOTYPE No data available