OBO ID: CHEBI:149696
Term Name: 10058-F4 Search Ontology:
Synonyms:
  • 10058F4
  • 5-(4-ethylbenzylidene)-2-mercapto-1,3-thiazol-4(5H)-one
  • 5-(4-ethylbenzylidene)-2-sulfanylidene-1,3-thiazolidin-4-one
  • 5-(4-ethylbenzylidene)-2-thioxothiazolidin-4-one
  • 5-[(4-ethylphenyl)methylene]-2-thioxo-4-thiazolidinone
Definition: A member of the class of thiazolidinones that is 2-sulfanylidene-1,3-thiazolidin-4-one which is substituted at position 5 by a (4-ethylphenyl)methylidene group. It is a cell permeable inhibitor of c-Myc-Max dimerization and exhibits antitumour effects in vivo. It downregulates c-Myc expression and upregulates CDK inhibitors, p21 and p27 resulting in the inhibition of proliferation, induction of apoptosis and cell cycle arrest in G0/G1 phase.
References:
Ontology: Chebi
Relationships
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has_role:
PHENOTYPE No data available

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