OBO ID: CHEBI:145417
Term Name: rigosertib Search Ontology:
Synonyms:
  • (E)-ON 01910
  • [2-methoxy-5-({[(E)-2-(2,4,6-trimethoxyphenyl)ethenyl]sulfonyl}methyl)anilino]acetic acid
  • N-[2-methoxy-5-({[(E)-2-(2,4,6-trimethoxyphenyl)ethenyl]sulfonyl}methyl)phenyl]glycine
  • ON 01910
  • ON-01910
  • rigosertib
  • rigosertibum
Definition: An N-[2-methoxy-5-({[2-(2,4,6-trimethoxyphenyl)ethenyl]sulfonyl}methyl)phenyl]glycine in which the double bond has E-configuration. It is a non-ATP-competitive inhibitor of PLK1 with an IC50 of 9 nM and exhibits anti-cancer properties.
References:
Ontology: ChEBI  ( EBI )
PHENOTYPE No data available