ZFIN ChEBI: andrastin D

OBO ID: CHEBI:142874

Term Name:	andrastin D		Search Ontology:
Synonyms:	methyl (5beta,8alpha,9beta,10alpha,13alpha)-15-hydroxy-4,4,8,12,16-pentamethyl-3,17-dioxoandrosta-11,15-diene-14-carboxylate methyl 15-hydroxy-4,4,8alpha,12,16-pentamethyl-3,17-dioxo-5beta,9beta,10alpha,13alpha-androsta-11,15-diene-14-carboxylate
Definition:	A 3-oxo steroid that is andrastin C in which the acetoxy group at the 3beta position has undergone formal oxidative cleavage to afford the corresponding 3-oxo derivative. A farnesyltransferase inhibitor produced by Penicillium roqueforti, a filamentous fungus involved in the ripening of several kinds of blue cheeses.
References:	CAS:184432-08-4 KNApSAcK:C00016286 PMID:15826038 PMID:9031675
Ontology:	ChEBI ( EBI )

Relationships

is a type of:	3-oxo steroid 5beta steroid 15-hydroxy steroid 17-oxo steroid enol ... Show All 7 Terms 3-oxo steroid 5beta steroid 15-hydroxy steroid 17-oxo steroid enol meroterpenoid methyl ester Show first 5 Terms
has_role:	EC 2.5.1.58 (protein farnesyltransferase) inhibitor Penicillium metabolite EC 2.5.1.58 (protein farnesyltransferase) inhibitor Penicillium metabolite Show first 5 Terms
inverse has_functional_parent:	andrastin E andrastin F andrastin E andrastin F Show first 5 Terms
inverse is_conjugate_base_of:	andrastin D(1-) andrastin D(1-) Show first 5 Terms
is_conjugate_acid_of:	andrastin D(1-) andrastin D(1-) Show first 5 Terms

PHENOTYPE No data available