OBO ID: CHEBI:142431

Term Name:	praliciguat		Search Ontology:
Synonyms:	1,1,1,3,3,3-hexafluoro-2-[({5-fluoro-2-[1-(2-fluorobenzyl)-5-(1,2-oxazol-3-yl)-1H-pyrazol-3-yl]pyrimidin-4-yl}amino)methyl]propan-2-ol IW-1973 praliciguat praliciguatum
Definition:	A member of the class of pyrazoles that is 5-fluoro-2-(1H-pyrazol-3-yl)pyrimidine which is substituted by a 2-fluorobenzyl group at position 1, 1,2-oxazol-3-yl group at position 5, and by a [3,3,3-trifluoro-2-hydroxy-2-(trifluoromethyl)propyl]nitrilo group at position 4. It is a soluble guanylate cyclase stimulator under clinical development for the treatment of heart failure with preserved ejection fraction.
References:	CAS:1628730-49-3 PMID:29281143 PMID:29643251 Patent:WO2014144100 Patent:WO2017095697 Reaxys:27468841
Ontology:	ChEBI  ( EBI )