OBO ID: CHEBI:140158

Term Name:	cyclosporin A metabolite M8		Search Ontology:
Synonyms:	(3S,6S,9S,12R,15S,18S,21S,24S,30S,33S)-33-[(1R,2R,4E)-1,6-dihydroxy-2-methylhex-4-en-1-yl]-30-ethyl-9-(2-hydroxy-2-methylpropyl)-6,18,24-triisobutyl-3,21-diisopropyl-1,4,7,10,12,15,19,25,28-nonamethyl-1,4,7,10,13,16,19,22,25,28,31-undecaazacyclotritriacon AM19 cyclosporin A metabolite AM19 cyclosporin metabolite AM19 cyclosporin metabolite M8 M8
Definition:	A cyclosporin A derivative that is cyclosporin A in which residue 1 [(2S,3R,4R,6E)-3-hydroxy-4-methyl-2-(methylamino)oct-6-enoic acid] has undergone allylic oxidation to give the corresponding primary allylic alcohol, and in which residue 9 (N-methylleucine) has undergone oxidation so as to introduce a hydroxy group at the carbon bearing the two methyl groups.
References:	PMID:1362930 PMID:1895678 PMID:1943052 PMID:1971578 PMID:2642763 PMID:2944258 PMID:2948307 PMID:3311467 PMID:3538573
Ontology:	ChEBI  ( EBI )