OBO ID: CHEBI:139271
Term Name: 6beta-hydroxycortisol Search Ontology:
Synonyms:
  • (6beta,11beta)-6,11,17,21-tetrahydroxypregn-4-ene-3,20-dione
  • 6beta,11beta,17,21-tetrahydroxypregn-4-ene-3,20-dione
  • 6beta,11beta,17alpha,21-tetrahydroxypregn-4-ene-3,20-dione
  • 6beta-HO-cortisol
  • 6beta-hydroxycortisol
  • 6beta-OH-cortisol
  • NSC 76163
Definition: A C21-steroid that is cortisol bearing an additional hydroxy substituent at the 6beta-position. In humans, it is produced as a metabolite of cortisol by cytochrome p450-3A4 (CYP3A4, an important enzyme involved in the metabolism of a variety of exogenous and endogenous compounds) and can be used to detect moderate and potent CYP3A4 inhibition in vivo.
References:
Ontology: Chebi
PHENOTYPE No data available