OBO ID: CHEBI:139269
Term Name: 6beta-hydroxycortisone Search Ontology:
Synonyms:
  • 6beta,17,21-trihydroxypregn-4-ene-3,11,20-trione
  • 6beta-17alpha,21-trihydroxypregn-4-ene-3,11,20-trione
  • 6beta-hydroxycortisone
Definition: A C21-steroid that is cortisone bearing an additional hydroxy substituent at the 6beta-position. It is produced as a metabolite of cortisol by cytochrome p450-3A4 (CYP3A4, an important enzyme involved in the metabolism of a variety of exogenous and endogenous compounds) and can be used to detect moderate and potent CYP3A4 inhibition in vivo.
References:
Ontology: Chebi
PHENOTYPE No data available