OBO ID: CHEBI:135900

Term Name:	demoxytocin		Search Ontology:
Synonyms:	1-(3-mercaptopropionic acid)-oxytocin 1-{[(4R,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-[(2S)-butan-2-yl]-16-(4-hydroxybenzyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-4-yl]carbonyl}-L-prolyl-L-leucylglycinamide deaminooxytocin demoxitocina demoxytocin demoxytocine demoxytocinum desamino oxytocin desamino-oxytocin desaminooxytocin ODA 914 ODA-914 Odeax Sandopart Sandopral
Definition:	A heterodetic cyclic peptide that is the synthetic analog of the peptide hormone oxytocin where the free amino group in the half-cystine residue is replaced by hydrogen. The mechanism of action and pharmacological properties of demoxytocin and oxytocin are similar. The drug affects the permeability of the cell membrane, increasing the content of calcium ions in smooth muscle cells, thereby increasing its contraction. It stimulates the contraction of smooth muscles of the uterus, as well as stimulating the contraction of myoepithelial cells of the mammary gland, and enhances the secretion of milk.
References:	CAS:113-78-0 Chemspider:395815 DrugBank:DB13798 Drug_Central:3126 KEGG:D07228 PMID:29309759 PMID:393119 PMID:428195 PMID:4446103 PMID:445976 PMID:468056 PMID:4740061 PMID:4887636 PMID:5020079 PMID:5081052 PMID:5152525 PMID:5303864 PMID:530450 PMID:5470650 PMID:5487933 PMID:5498369 PMID:5537710 PMID:555036 PMID:5561292 PMID:5678655 PMID:5756152 PMID:5756153 PMID:6575575 PMID:6575576 PMID:700921 PMID:7460491 PMID:756601 PMID:7650072 PMID:9083475 PMID:940106 Wikipedia:Demoxytocin
Ontology:	ChEBI  ( EBI )