Term Name: | mitochondrial iron-sulfur cluster assembly complex |
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Synonyms: | |
Definition: | A protein complex consisting of frataxin, cysteine desulfurase, an accessory protein and a Fe-S scaffold protein. In human these genes correspond to FXN, NFS1, ISD11 and ISCU respectively. This complex assembles Fe-S clusters onto the scaffolding protein using the substrates ferrous iron, electrons, and sulfur from l-cysteine. |
Ontology: | GO: Cellular Component [GO:0099128] QuickGO AmiGO |