Term Name: | Rho guanyl-nucleotide exchange factor activity |
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Synonyms: | Rho guanine nucleotide exchange factor, RhoGEF |
Definition: | Stimulates the exchange of guanyl nucleotides associated with a GTPase of the Rho family. Under normal cellular physiological conditions, the concentration of GTP is higher than that of GDP, favoring the replacement of GDP by GTP in association with the GTPase. |
Ontology: | GO: Molecular Function [GO:0005089] QuickGO AmiGO |