Term Name: amyloidosis
Synonyms: amyloid disease
Definition: A disease of metabolsism that is characterized by extracellular tissue deposition of mis-folded amyloid fibrils built up by twisted protofilaments, deposited in the spaces between the cells of vital organs, causing disruption of organ tissue structure and function. These deposits may result in a wide range of clinical manifestations depending upon their type, location, and the amount of deposition.
Ontology: Human Disease [DOID:9120]   (DOID:9120)

Relationships
is a type of: disease of metabolism
has subtype: apolipoprotein A-IV associated amyloidosis cerebral amyloid angiopathy dialysis-related amyloidosis familial visceral amyloidosis immunoglobulin heavy chain amyloidosis immunoglobulin heavy-and-light chain immunoglobulin light chain amyloidosis primary cutaneous amyloidosis serum amyloid A amyloidosis transthyretin amyloidosis variant ABeta2M amyloidosis wild-type amyloidosis