Term Name: EC 1.5.1.3 (dihydrofolate reductase) inhibitor
Synonyms: 7,8-dihydrofolate reductase inhibitor, 7,8-dihydrofolate reductase inhibitors, DHFR inhibitor, DHFR inhibitors, dihydrofolate reductase (EC 1.5.1.3) inhibitor, dihydrofolate reductase (EC 1.5.1.3) inhibitors, dihydrofolate reductase inhibitor, dihydrofolate reductase inhibitors, dihydrofolic acid reductase inhibitor, dihydrofolic acid reductase inhibitors, dihydrofolic reductase inhibitor, dihydrofolic reductase inhibitors, EC 1.5.1.3 (dihydrofolate reductase) inhibitors, EC 1.5.1.3 inhibitor, EC 1.5.1.3 inhibitors, folic acid reductase inhibitor, folic acid reductase inhibitors, folic reductase inhibitor, folic reductase inhibitors, NADPH-dihydrofolate reductase inhibitor, NADPH-dihydrofolate reductase inhibitors, tetrahydrofolate dehydrogenase inhibitor, tetrahydrofolate dehydrogenase inhibitors
Definition: An EC 1.5.1.* (oxidoreductase acting on donor CH-NH group, NAD(+) or NADP(+) as acceptor) inhibitor that interferes with the action of dihydrofolate reductase (EC 1.5.1.3).
Ontology: Chebi [CHEBI:50683]

Relationships
is a type of: antifolate EC 1.5.1.* (oxidoreductase acting on donor CH-NH group, NAD(+) or NADP(+) as acceptor) inhibitor
inverse has_role: (R)-iclaprim (S)-iclaprim 4-aminofolic acid brodimoprim cycloguanil iclaprim methotrexate methotrexate disodium O-(chloroacetylcarbamoyl)fumagillol pemetrexed pemetrexed disodium pemetrexed disodium heptahydrate pralatrexate proguanil pyrimethamine triclosan trimethoprim