Term Name: 680C91
Synonyms: 6-fluoro-3-[(E)-2-(pyridin-3-yl)vinyl]-1H-indole
Definition: A fluoroindole that is 6-fluoroindole in which the hydrogen at position 3 has been replaced by a 2-(pyridin-3-yl)vinyl group (trans configuration). It is a selective inhibitor of tryptophan 2,3-dioxygenase (TDO), which directs the conversion of trypophan to kynurenin.
Ontology: Chebi [CHEBI:131851]

Relationships
is a type of: fluoroindole olefinic compound pyridines
has_role: EC 1.13.11.11 (tryptophan 2,3-dioxygenase) inhibitor