| Term Name: | 3-hydroxy-3-methylglutaric acid |
|---|---|
| Synonyms: | (S)-3-Hydroxy-3-methylglutaric acid, (S)-Meglutol, 3-HYDROXY-3-METHYL-GLUTARIC ACID, 3-Hydroxy-3-methylpentanedioic acid, beta-hydroxy-beta-methylglutaric acid, Dicrotalic acid, meglutol, meglutolum |
| Definition: | A dicarboxylic acid that is glutaric acid in which one of the two hydrogens at position 3 is substituted by a hydroxy group, while the other is substituted by a methyl group. It has been found to accumulate in urine of patients suffering from HMG-CoA lyase (3-hydroxy-3-methylglutaryl-CoA lyase, EC 4.1.3.4) deficiency. It occurs as a plant metabolite in Crotalaria dura. |
| Ontology: | ChEBI [CHEBI:16831] ( EBI ) |