Term: midbrain apoptotic process
Note: This page represents a term created by the combination ("post-composition") of two ontology terms. For more information on the individual terms, click the hyperlinked name.
Name: midbrain
Synonyms: mesencephalon
Definition: The brain region between the forebrain anteriorly and the hindbrain posteriorly, including the tectum dorsally and the midbrain tegmentum ventrally.
Ontology: Anatomy Ontology [ZFA:0000128]
Name: apoptotic process
Synonyms: apoptosis, apoptosis activator activity, apoptosis signaling, apoptotic cell death, apoptotic program, apoptotic programmed cell death, caspase-dependent programmed cell death, cell suicide, cellular suicide, commitment to apoptosis, induction of apoptosis, induction of apoptosis by p53, programmed cell death by apoptosis, signaling (initiator) caspase activity, type I programmed cell death
Definition: A programmed cell death process which begins when a cell receives an internal (e.g. DNA damage) or external signal (e.g. an extracellular death ligand), and proceeds through a series of biochemical events (signaling pathway phase) which trigger an execution phase. The execution phase is the last step of an apoptotic process, and is typically characterized by rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died.
Ontology: GO: Biological Process [GO:0006915]    QuickGO    AmiGO