Morpholino

MO7-tp53

ID

ZDB-MRPHLNO-100415-11

Name

MO7-tp53

Previous Names

MO15-tp53
p53 MO (1)

Target

tp53 (1)

Sequence

5' - TCTTGGCTGTCGTTTTGCGCCATTG - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

None

Genome Resources

None

Target Location

Genomic Features

No data available

Expression

Gene expression in Wild Types + MO7-tp53

Expressed Gene	Anatomy	Figures
fabp1a	liver	Fig. 5 from Yuan et al., 2015
myb	hematopoietic stem cell post-vent region hematopoietic stem cell	Fig. 5 from He et al., 2017 Fig. S12 from Jia et al., 2015

Phenotype

Phenotype resulting from MO7-tp53

No data available

Phenotype of all Fish created by or utilizing MO7-tp53

Phenotype	Fish	Conditions	Figures
presumptive ventral mesoderm tbx6 expression decreased amount, abnormal	cdkn2aip^{cas009/cas009} + MO1-wnt8a + MO2-wnt8a + MO7-tp53	control	Fig. 4 from He et al., 2017
presumptive ventral mesoderm cdx4 expression decreased amount, abnormal	cdkn2aip^{cas009/cas009} + MO1-wnt8a + MO2-wnt8a + MO7-tp53	control	Fig. 4 from He et al., 2017
canonical Wnt signaling pathway decreased process quality, abnormal	cdkn2aip^{cas009/cas009} + MO1-wnt8a + MO2-wnt8a + MO7-tp53	control	Fig. 4 from He et al., 2017
definitive hemopoiesis decreased occurrence, abnormal	cdkn2aip^{cas009/cas009} + MO7-tp53	control	Fig. 5 from He et al., 2017
hematopoietic stem cell myb expression decreased amount, abnormal	cdkn2aip^{cas009/cas009} + MO7-tp53	control	Fig. 5 from He et al., 2017
liver fabp1a expression spatial pattern, ameliorated	cebpa^rj31/+ + MO7-tp53	standard conditions	Fig. 5 from Yuan et al., 2015
liver size, ameliorated	irf2bp2a^{zf3610/zf3610} + MO7-tp53	standard conditions	Fig. 3 from Yan et al., 2022
blood island hematopoietic stem cell decreased amount, abnormal	kri1^{cas002/cas002} + MO7-tp53	standard conditions	Fig. S12 from Jia et al., 2015
presumptive ventral mesoderm cdx4 expression decreased amount, abnormal	TU + MO1-cdkn2aip + MO1-wnt8a + MO2-wnt8a + MO7-tp53	control	Fig. 4 from He et al., 2017
canonical Wnt signaling pathway decreased process quality, abnormal	TU + MO1-cdkn2aip + MO1-wnt8a + MO2-wnt8a + MO7-tp53	control	Fig. 4 from He et al., 2017
presumptive ventral mesoderm tbx6 expression decreased amount, abnormal	TU + MO1-cdkn2aip + MO1-wnt8a + MO2-wnt8a + MO7-tp53	control	Fig. 4 from He et al., 2017
hematopoietic multipotent progenitor cell decreased amount, abnormal	WT + MO1-ube2ia + MO2-ube2ib + MO7-tp53	standard conditions	Fig. 1 from Yuan et al., 2015
apoptotic process decreased occurrence, abnormal	WT + MO1-sumo1 + MO1-sumo2b + MO1-sumo3a + MO7-tp53	standard conditions	Fig. 4 from Yuan et al., 2010
hematopoietic multipotent progenitor cell decreased amount, abnormal	WT + MO1-sumo1 + MO1-sumo2b + MO1-sumo3a + MO7-tp53	standard conditions	Fig. 1 from Yuan et al., 2015

Citations