Morpholino

MO1-en2a

ID

ZDB-MRPHLNO-060930-2

Name

MO1-en2a

Previous Names

MO1-eng2a

Target

en2a (1)

Sequence

5' - CGCTCTGCTCATTCTCATCCATGCT - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

None

Genome Resources

None

Target Location

Genomic Features

No data available

Expression

Gene expression in Wild Types + MO1-en2a

Expressed Gene	Anatomy	Figures
en2b	midbrain hindbrain boundary midbrain hindbrain boundary neural keel optic stalk otic vesicle	Fig. 1 from Scholpp et al., 2001

Phenotype

Phenotype resulting from MO1-en2a

Phenotype	Fish	Figures
optic tectum decreased size, abnormal	WT + MO1-en2a	Fig. 1 from Scholpp et al., 2001

Phenotype of all Fish created by or utilizing MO1-en2a

Phenotype	Fish	Conditions	Figures
optic tectum decreased size, abnormal	WT + MO1-en2a	standard conditions	Fig. 1 from Scholpp et al., 2001
brain lacks all parts of type midbrain hindbrain boundary, abnormal	WT + MO1-en2a + MO1-en2b	standard conditions	Fig. 1, Fig. 2 from Scholpp et al., 2001
brain lacks all parts of type optic tectum, abnormal	WT + MO1-en2a + MO1-en2b	standard conditions	Fig. 1, Fig. 2 from Scholpp et al., 2001
midbrain-hindbrain boundary development disrupted, abnormal	WT + MO1-en2a + MO1-en2b	standard conditions	Fig. 1, Fig. 2 from Scholpp et al., 2001
midbrain development disrupted, abnormal	WT + MO1-en2a + MO1-en2b	standard conditions	Fig. 2 from Scholpp et al., 2001
brain apoptotic, abnormal	WT + MO1-en2a + MO2-grhl2b	standard conditions	Fig. 3 from Dworkin et al., 2012
rhombomere pax6a expression increased distribution, abnormal	WT + MO1-en2a + MO1-en2b + MO1-otx2a + MO1-otx2b	standard conditions	Fig. 11 from Albuixech-Crespo et al., 2017
forebrain pax6a expression increased distribution, abnormal	WT + MO1-en2a + MO1-en2b + MO1-otx2a + MO1-otx2b	standard conditions	Fig. 11 from Albuixech-Crespo et al., 2017
hindbrain pax6a expression increased distribution, abnormal	WT + MO1-en2a + MO1-en2b + MO1-otx2a + MO1-otx2b	standard conditions	Fig. 11 from Albuixech-Crespo et al., 2017
midbrain hindbrain boundary wnt1 expression absent, abnormal	WT + MO1-en2a + MO1-en2b + MO1-otx2a + MO1-otx2b	standard conditions	Fig. 11 from Albuixech-Crespo et al., 2017
midbrain pax6a expression increased distribution, abnormal	WT + MO1-en2a + MO1-en2b + MO1-otx2a + MO1-otx2b	standard conditions	Fig. 11 from Albuixech-Crespo et al., 2017
midbrain wnt1 expression decreased amount, abnormal	WT + MO1-en2a + MO1-en2b + MO1-otx2a + MO1-otx2b	standard conditions	Fig. 11 from Albuixech-Crespo et al., 2017
zona limitans intrathalamica shha expression absent, abnormal	WT + MO1-en2a + MO1-en2b + MO1-otx2a + MO1-otx2b	standard conditions	Fig. 11 from Albuixech-Crespo et al., 2017

Citations