Morpholino

MO2-dlx3b

ID

ZDB-MRPHLNO-050208-13

Name

MO2-dlx3b

Previous Names

dlx3-1 MO (1)

Target

dlx3b

Sequence

5' - ATATGTCGGTCCACTCATCCTTAAT - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

This is a dlx3b translation blocker. Mackereth et al. (2005) shows an extra T near the 3'-end due to a misprint. The correct sequence is displayed here.

Genome Resources

None

Target Location

Genomic Features

No data available

Expression

Gene expression in Wild Types + MO2-dlx3b

Expressed Gene	Anatomy	Figures
anxa5b	olfactory placode	Fig. 4 from Solomon et al., 2002
dlx3b	olfactory field olfactory placode otic placode otic vesicle pharyngeal arch	Fig. 8 from Mackereth et al., 2005 Fig. 6 from Solomon et al., 2002
dlx4b	olfactory field otic placode	Fig. 6 from Solomon et al., 2002
eya1	anterior lateral line placode olfactory placode otic vesicle posterior lateral line placode somite	Fig. 4 from Solomon et al., 2002
pax2a	midbrain hindbrain boundary neural keel midbrain hindbrain boundary neural rod otic placode pronephric mesoderm	Fig. 8 from Mackereth et al., 2005 Fig. 5 from Solomon et al., 2002
pax8	otic placode pronephric mesoderm	Fig. 5 from Solomon et al., 2002

Phenotype

Phenotype resulting from MO2-dlx3b

Phenotype	Fish	Figures
olfactory placode development process quality, abnormal	WT + MO2-dlx3b	Fig. 4 from Solomon et al., 2002
otic vesicle decreased size, abnormal	WT + MO2-dlx3b	Fig. 2 from Solomon et al., 2002
otic vesicle development process quality, abnormal	WT + MO2-dlx3b	Fig. 4 from Solomon et al., 2002
otolith decreased amount, abnormal	WT + MO2-dlx3b	Fig. 2 from Solomon et al., 2002

Phenotype of all Fish created by or utilizing MO2-dlx3b

Phenotype	Fish	Conditions	Figures
otic vesicle decreased size, abnormal	WT + MO2-dlx3b	standard conditions	Fig. 2 from Solomon et al., 2002
otic vesicle development process quality, abnormal	WT + MO2-dlx3b	standard conditions	Fig. 4 from Solomon et al., 2002
olfactory placode development process quality, abnormal	WT + MO2-dlx3b	standard conditions	Fig. 4 from Solomon et al., 2002
otolith decreased amount, abnormal	WT + MO2-dlx3b	standard conditions	Fig. 2 from Solomon et al., 2002
otolith absent, abnormal	WT + MO2-dlx3b + MO4-dlx4b	standard conditions	Fig. 2 from Solomon et al., 2002
olfactory placode formation arrested, abnormal	WT + MO2-dlx3b + MO4-dlx4b	standard conditions	Fig. 5 from Solomon et al., 2002
otic placode pax2a expression absent, abnormal	WT + MO2-dlx3b + MO4-dlx4b	standard conditions	Fig. 6 from Sun et al., 2007
otic vesicle development process quality, abnormal	WT + MO2-dlx3b + MO4-dlx4b	standard conditions	Fig. 4 from Solomon et al., 2002
otic vesicle decreased size, abnormal	WT + MO2-dlx3b + MO4-dlx4b	standard conditions	Fig. 2 from Solomon et al., 2002
olfactory placode development process quality, abnormal	WT + MO2-dlx3b + MO4-dlx4b	standard conditions	Fig. 4 from Solomon et al., 2002
otic vesicle development process quality, abnormal	WT + MO2-dlx3b + MO5-dlx4b	standard conditions	Fig. 4 from Solomon et al., 2002
olfactory placode development process quality, abnormal	WT + MO2-dlx3b + MO5-dlx4b	standard conditions	Fig. 4 from Solomon et al., 2002
otolith absent, abnormal	WT + MO2-dlx3b + MO5-dlx4b	standard conditions	Fig. 2 from Solomon et al., 2002
olfactory placode formation arrested, abnormal	WT + MO2-dlx3b + MO5-dlx4b	standard conditions	Fig. 5 from Solomon et al., 2002
otic vesicle decreased size, abnormal	WT + MO2-dlx3b + MO5-dlx4b	standard conditions	Fig. 2 from Solomon et al., 2002
otic vesicle decreased size, abnormal	WT + MO2-dlx3b + MO6-pax8 + MO7-pax8	standard conditions	Fig. 8 from Mackereth et al., 2005
otic vesicle lacks all parts of type hair cell, abnormal	WT + MO2-dlx3b + MO6-pax8 + MO7-pax8	standard conditions	Fig. 8 from Mackereth et al., 2005
otic vesicle lacks all parts of type otolith, abnormal	WT + MO2-dlx3b + MO6-pax8 + MO7-pax8	standard conditions	Fig. 8 from Mackereth et al., 2005
otic vesicle morphogenesis process quality, abnormal	WT + MO2-dlx3b + MO6-pax8 + MO7-pax8	standard conditions	Fig. 8 from Mackereth et al., 2005

Citations