ZFIN ID: ZDB-GENE-990415-30
Gene Name: activated leukocyte cell adhesion molecule a
Gene Symbol: alcama
Previous Names: alcam (1), cd166 (1), DM-GRASP (1), neurolin-a (1), neurolin (1), zn5 / zn-5 antigen (1), zn8 / zn-8 antigen
Location: Chr: 10   Details
Nomenclature History
GENE EXPRESSION
All Expression Data: 158 figures from 89 publications
Directly Submitted Expression Data: 6 figures (14 images) from Thisse et al., 2004 [MGC:55230]
Wild-type Stages, Structures: Segmentation:1-4 somites (10.33h-11.66h) to Adult (90d-730d, breeding adult)
  abducens motor nucleus, adaxial cell, anterior commissure, atrioventricular canal endocardium (all 103) expand
Curated Microarray Expression: GEO (1)
MUTANTS AND TARGETED KNOCKDOWNS
Knockdown reagents: MO1-alcama (1), MO2-alcama (1), MO3-alcama (1), MO4-alcama (1), MO5-alcama (1)

Allele Type Mutagen Suppliers
la011841Tg Transgenic Insertion DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa12510 Point Mutation ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • European Zebrafish Resource Center (EZRC) (order this)
  • PHENOTYPE
    Data: 6 figures from 4 publications
    Observed in: ceratohyal cartilage, eye, heart looping, hyosymplectic cartilage (all 14) expand
    DISEASE ASSOCIATED WITH alcama HUMAN ORTHOLOG No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process axonogenesis (more)
    Cellular Component axon (more)
    Molecular Function identical protein binding (more)
    GO Terms (all 15)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR003006 (1)
  • InterPro:IPR003598 (1)
  • InterPro:IPR003599 (1)
  • InterPro:IPR007110 (1)
  • InterPro:IPR013106 (1)
  • InterPro:IPR013162 (1)
  • InterPro:IPR013783 (1)
  • PROSITE:PS00290 (1)
  • PROSITE:PS50835 (1)
  • Pfam:PF08205 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA alcama-001 (1) 3112
    ottdart00000004183 (1) 1145
     Withdrawn Transcriptsextinct
    GENE PRODUCT DESCRIPTION
    ANTIBODIES
    Ab1-alcama (1), Ab2-alcama (1), Ab3-alcama (1), zn-5 (1), zn-8 (1)
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM alcama
    Tg(nkx2.3:alcama-EGFP)
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    alcama Contained in: [BAC] DKEY-222J15 (1) (order this)
    [PAC] BUSM1-17K08 (1) (order this), BUSM1-25N23 (1) (order this), BUSM1-39L02 (1) (order this), BUSM1-71O15 (1) (order this)
    alcama Encodes: [cDNA] cssl:d215 (1), cssl:d822 (1), MGC:55230 (1) (order this), MGC:85602 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_131000 (1) 2057 bp
    Genomic GenBank:BX537347 (1) 197064 bp
    Select Tool
    Polypeptide UniProtKB:F1QWY8 (1) 573 aa
    Sequence Clusters UniGene:20912 (1)
    Sequence Information (all 44)
    OTHER alcama GENE PAGES
  • Gene:30194 (1)
  • VEGA:OTTDARG00000004010 (1)
  • VEGA:OTTDARG00000008167 (1)
  • ORTHOLOGY
      Evidence
    Species Symbol Chr (Position) Accession # AA CL
    Zebrafish alcama 10  
    Human ALCAM 3 (3q13.1)
  • OMIM:601662
  • Gene:214
  • Mouse Alcam 16 ( 32.88 cM)
  • MGI:1313266
  • Gene:11658
  • Orthology Details
    CITATIONS (137)