Research
General Information
ZIRC
ZFIN ID: ZDB-GENE-990415-30
Gene Name: activated leukocyte cell adhesion molecule a
Gene Symbol: alcama
Previous Names: alcam (1), cd166 (1), DM-GRASP (1), neurolin (1), neurolin-a (1), zn5 / zn-5 antigen (1), zn8 / zn-8 antigen
Location: Chr: 10   Details
Nomenclature History
GENE EXPRESSION
All Expression Data: 142 figures from 82 publications
Directly Submitted Expression Data: 6 figures (14 images) from Thisse et al., 2004 [MGC:55230]
Wild-type Stages, Structures: Segmentation:1-4 somites (10.33h-11.66h) to Adult (90d-730d, breeding adult)
  adaxial cell, anterior commissure, atrioventricular canal endocardium, cephalic musculature (all 85) expand
Curated Microarray Expression: GEO (1)
MUTANTS AND TARGETED KNOCKDOWNS
Alleles: la011841Tg, sa12510
Knockdown reagents: MO1-alcama (1), MO2-alcama (1), MO3-alcama (1), MO4-alcama (1), MO5-alcama (1)
PHENOTYPE
Data: 5 figures from 3 publications
Observed in: ceratohyal cartilage, eye, heart looping, hyosymplectic cartilage (all 11) expand
GENE ONTOLOGY
Ontology GO Term
Biological Process axonogenesis (more)
Cellular Component axon (more)
Molecular Function identical protein binding (more)
GO Terms (all 12)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR003006 (1)
  • InterPro:IPR003596 (1)
  • InterPro:IPR003598 (1)
  • InterPro:IPR003599 (1)
  • InterPro:IPR007110 (1)
  • InterPro:IPR013162 (1)
  • InterPro:IPR013783 (1)
  • PROSITE:PS00290 (1)
  • PROSITE:PS50835 (1)
  • Pfam:PF08205 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA alcama-001 (1) 3112
    ottdart00000004183 (1) 1145
     Withdrawn Transcriptsextinct
    GENE PRODUCT DESCRIPTION
    ANTIBODIES
    Ab1-alcama (1), Ab2-alcama (1), Ab3-alcama (1), zn-5 (1), zn-8 (1)
    CONSTRUCTS WITH SEQUENCES FROM alcama
    Tg(nkx2.3:alcama-EGFP)
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    alcama Contained in: [BAC] DKEY-222J15 (1)
    [PAC] BUSM1-17K08 (1) (order this), BUSM1-25N23 (1) (order this), BUSM1-39L02 (1) (order this), BUSM1-71O15 (1) (order this)
    alcama Encodes: [cDNA] cssl:d215 (1), cssl:d822 (1), MGC:55230 (1) (order this), MGC:85602 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_131000 (1) 2057 bp
    Genomic GenBank:BX537347 (1) 197064 bp
    Select Tool
    Polypeptide UniProtKB:F1QWY8 (1) 573 aa
    Sequence Clusters UniGene:20912 (1)
    Sequence Information (all 44)
    OTHER alcama GENE PAGES
  • Gene:30194 (1)
  • VEGA:OTTDARG00000004010 (1)
  • VEGA:OTTDARG00000008167 (1)
  • Ensembl(Zv9):ENSDARG00000026531 (1)
  • ORTHOLOGY
      Evidence
    Species Symbol Chr (Position) Accession # AA CL
    Zebrafish alcama 10  
    Human ALCAM 3 (3q13.1)
  • OMIM:601662
  • Gene:214
  • Mouse Alcam 16 ( 32.88 cM)
  • MGI:1313266
  • Gene:11658
  • Orthology Details
    CITATIONS (132)