ZFIN ID: ZDB-GENE-980526-306
Gene Name: muscle segment homeobox 3
Gene Symbol: msx3
Previous Names: msx-c, msxc (1), etID309953.13 (1), msh-C, mshC, zgc:86596 (1)
Location: Chr: 13 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 68 figures from 43 publications
Directly Submitted Expression Data: 7 figures (19 images) from Thisse et al., 2005 [eu507]
Wild-type Stages, Structures: Gastrula:75%-epiboly (8.0h-9.0h) to Adult (90d-730d, breeding adult)
  anterior crista, anterior crista primordium, ball epidermis, brain dorsal region (all 50) expand
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS 
Allele Type Mutagen Suppliers
mn0245Gt Transgenic Insertion DNA
tud18Gt Transgenic Insertion DNA
  • European Zebrafish Resource Center (EZRC) (order this)
  • Targeting reagents: MO1-msx3 (1)
    PHENOTYPE
    Data: 2 figures from Phillips et al., 2006
    Observed in: cartilage development, cranial cartilage, embryonic viscerocranium morphogenesis, post-vent region
    DISEASE ASSOCIATED WITH msx3 HUMAN ORTHOLOG No data available
    GENE ONTOLOGY 
    Ontology GO Term
    Biological Process otic placode formation (more)
    Cellular Component nucleus (more)
    Molecular Function DNA binding (more)
    GO Terms (all 6)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001356 (1)
  • InterPro:IPR009057 (1)
  • InterPro:IPR017970 (1)
  • InterPro:IPR020479 (1)
  • PROSITE:PS00027 (1)
  • PROSITE:PS50071 (1)
  • Pfam:PF00046 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA msx3-001 (1) 2028
    GENE PRODUCT DESCRIPTION
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM msx3 No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS 
    msx3Contained in: [BAC] CH211-217G15 (1) (order this), DKEYP-85D1
    msx3Encodes: [EST] eu507 (1), fc66g03 (1)
    [cDNA] MGC:86596 (order this)
    SEQUENCE INFORMATION 
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_131272 (1) 2029bp
    Genomic GenBank:CR589879 201310bp Blast at MegaBLAST
    Polypeptide UniProtKB:Q6IQV1 (1) 274aa
    Sequence Clusters UniGene:32741 (1)
    Sequence Information (all 23)
    OTHER msx3 GENE PAGES 
  • Gene:30526 (1)
  • VEGA:OTTDARG00000001892 (1)
  • Ensembl(GRCz10):ENSDARG00000015674 (1)
  • ORTHOLOGY for msx3 (Chr: 13) 
    Species Symbol Chromosome Accession # Evidence
    Mouse Msx3 7
  • MGI:106587
  • Gene:17703
  • Amino acid sequence comparison (2)
    Conserved genome location (synteny) (2)
    Download Curated Orthology
    CITATIONS (91)