Gene
llgl1
- ID
- ZDB-GENE-060825-69
- Name
- LLGL scribble cell polarity complex component 1
- Symbol
- llgl1 Nomenclature History
- Previous Names
-
- zgc:153337
- Type
- protein_coding_gene
- Location
- Chr: 3 Mapping Details/Browsers
- Description
- Predicted to have GTPase activator activity; Rab GTPase binding activity; and myosin II binding activity. Involved in cell projection assembly; regulation of Notch signaling pathway; and sensory system development. Localizes to basolateral plasma membrane. Is expressed in central nervous system; eye; head; and retina. Orthologous to human LLGL1 (LLGL scribble cell polarity complex component 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 3 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 25 figures from 5 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR013577 | Lethal giant larvae homologue 2 |
| Domain | IPR013905 | Lethal giant larvae (Lgl)-like, C-terminal domain |
| Family | IPR000664 | Lethal(2) giant larvae protein |
| Homologous_superfamily | IPR015943 | WD40/YVTN repeat-like-containing domain superfamily |
| Homologous_superfamily | IPR036322 | WD40-repeat-containing domain superfamily |
| Repeat | IPR001680 | WD40 repeat |
Domain Details Per Protein
| Protein | Length | Lethal(2) giant larvae protein | Lethal giant larvae homologue 2 | Lethal giant larvae (Lgl)-like, C-terminal domain | WD40 repeat | WD40-repeat-containing domain superfamily | WD40/YVTN repeat-like-containing domain superfamily |
|---|---|---|---|---|---|---|---|
|
UniProtKB:I0BWE2
|
1040 | ||||||
|
UniProtKB:A0A8M9PXW4
|
1040 | ||||||
|
UniProtKB:A0A8M2BBF6
|
1041 | ||||||
|
UniProtKB:E7FD67
|
1040 |
Interactions and Pathways
No data available
Plasmids
No data available