Gene
tusc3
- ID
- ZDB-GENE-050522-381
- Name
- tumor suppressor candidate 3
- Symbol
- tusc3 Nomenclature History
- Previous Names
-
- unm_sa1726
- zgc:110044 (1)
- Type
- protein_coding_gene
- Location
- Chr: 1 Mapping Details/Browsers
- Description
- Involved in magnesium ion transport. Predicted to localize to oligosaccharyltransferase complex. Human ortholog(s) of this gene implicated in autosomal recessive non-syndromic intellectual disability. Orthologous to human TUSC3 (tumor suppressor candidate 3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:110044 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| autosomal recessive intellectual developmental disorder 7 | Alliance | Intellectual developmental disorder, autosomal recessive 7 | 611093 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Oligosaccharyl transferase complex, subunit OST3/OST6 | Thioredoxin-like superfamily |
|---|---|---|---|
|
UniProtKB:A0A8M9QAV6
|
336 | ||
|
UniProtKB:Q503W5
|
300 |
Interactions and Pathways
No data available
Plasmids
No data available
- Comparative Orthology
- Alliance