Gene

farsa

ID

ZDB-GENE-050512-2

Name

phenylalanyl-tRNA synthetase subunit alpha

Symbol

farsa Nomenclature History

Previous Names

farsla (1)
wu:fj21a11
zgc:136506
zgc:158185

Type

protein_coding_gene

Location

Chr: 3 Mapping Details/Browsers

Description

Predicted to have phenylalanine-tRNA ligase activity. Predicted to be involved in phenylalanyl-tRNA aminoacylation and protein heterotetramerization. Predicted to localize to cytosol and phenylalanine-tRNA ligase complex. Orthologous to human FARSA (phenylalanyl-tRNA synthetase subunit alpha).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

4 figures from Giong et al., 2021

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With farsa Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
		?Rajab interstitial lung disease with brain calcifications 2	619013

Associated With farsa Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR002319	Phenylalanyl-tRNA synthetase
Domain	IPR006195	Aminoacyl-tRNA synthetase, class II
Domain	IPR040586	PheRS DNA binding domain 2
Domain	IPR040724	PheRS, DNA binding domain 1
Domain	IPR040725	PheRS, DNA binding domain 3
Family	IPR004529	Phenylalanyl-tRNA synthetase, class IIc, alpha subunit
Homologous_superfamily	IPR036390	Winged helix DNA-binding domain superfamily
Homologous_superfamily	IPR045864	Class II Aminoacyl-tRNA synthetase/Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL)