Gene

erlin1

ID
ZDB-GENE-050327-13
Name
ER lipid raft associated 1
Symbol
erlin1 Nomenclature History
Previous Names
  • fa10h05
  • fb19h05
  • wu:fa10h05
  • wu:fb19h05
  • zgc:110547
Type
protein_coding_gene
Location
Chr: 13 Mapping Details/Browsers
Description
Predicted to have cholesterol binding activity. Predicted to be involved in SREBP signaling pathway. Predicted to localize to endoplasmic reticulum membrane. Human ortholog(s) of this gene implicated in hereditary spastic paraplegia 62. Is expressed in liver. Orthologous to human ERLIN1 (ER lipid raft associated 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
3 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With erlin1 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
hereditary spastic paraplegia 62 Alliance Spastic paraplegia 62, autosomal recessive 615681
Associated With erlin1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001107 Band 7 domain
Family IPR033294 Erlin1/2
Homologous_superfamily IPR036013 Band 7/SPFH domain superfamily
Domain Details Per Protein
Protein Length Band 7 domain Band 7/SPFH domain superfamily Erlin1/2
UniProtKB:Q58EG2 342
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations