ZFIN ID: ZDB-GENE-040611-2
Gene Name: neuropilin 2a
Gene Symbol: nrp2a
Previous Name: npn-2A (1)
Location: Chr: 1 Details
Nomenclature History
GENE EXPRESSION
All Expression Data: 11 figures from 10 publications
Wild-type Stages, Structures: Segmentation:1-4 somites (10.33h-11.66h) to Larval:Day 5 (120.0h-144.0h, 3.9mm, 6 teeth)
  brain, cranial neural crest cell, hindbrain, post-vent region (all 12) expand
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Mutagen Suppliers
la021215Tg Transgenic Insertion DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa13255 Point Mutation ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • European Zebrafish Resource Center (EZRC) (order this)
  • sa13721 Point Mutation ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Targeting reagents: MO1-nrp2a (1), MO2-nrp2a (1), MO3-nrp2a (1), MO4-nrp2a (1)
    PHENOTYPE
    Data: Fig. 6 from Hermans et al., 2010
    Observed in: lymphangioblast cord, thoracic duct, vascular lymphangioblast
    DISEASE ASSOCIATED WITH nrp2a HUMAN ORTHOLOGNo data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process neural crest cell migration (more)
    Cellular Component integral component of membrane (more)
    Molecular Function metal ion binding (more)
    GO Terms (all 11)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000421 (1)
  • InterPro:IPR000859 (1)
  • InterPro:IPR000998 (1)
  • InterPro:IPR008979 (1)
  • InterPro:IPR013320 (1)
  • InterPro:IPR014648 (1)
  • InterPro:IPR022579 (1)
  • InterPro:IPR027143 (1)
  • PROSITE:PS01180 (1)
  • PROSITE:PS01285 (1)
  • PROSITE:PS01286 (1)
  • PROSITE:PS50022 (1)
  • PROSITE:PS50060 (1)
  • Pfam:PF00431 (1)
  • Pfam:PF00629 (1)
  • Pfam:PF00754 (1)
  • Pfam:PF11980 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA nrp2a-001 (1) 5278
    ncRNA nrp2a-003 (1) 1391
    mRNA ottdart00000062263 (1) 410
     Withdrawn Transcriptsextinct
    GENE PRODUCT DESCRIPTION
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM nrp2a No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    nrp2aContained in: [BAC] CH73-76B22 (1) (order this)
    [Fosmid] CH1073-331F6 (1) (order this), CH1073-435A3 (1) (order this)
    nrp2aEncodes: [cDNA] MGC:193601 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_212965 (1) 5316bp
    Genomic GenBank:CU469569 (1) 102276bp
    Select Tool
    Polypeptide UniProtKB:B3DFP6 (1) 927aa
    Sequence Clusters UniGene:29401 (1)
    Sequence Information (all 34)
    OTHER nrp2a GENE PAGES
  • Gene:405901 (1)
  • VEGA:OTTDARG00000037671 (1)
  • VEGA:OTTDARG00000042518 (1)
  • Ensembl(GRCz10):ENSDARG00000096546 (1)
  • ORTHOLOGY for nrp2a (Chr: 1)
    Species Symbol Chromosome Accession # Evidence
    Human NRP2 2
  • Gene:8828
  • OMIM:602070
  • HGNC:8005
  • Amino acid sequence comparison (3)
    Conserved genome location (synteny) (1)
    Mouse Nrp2 1
  • MGI:1100492
  • Gene:18187
  • Amino acid sequence comparison (2)
    Conserved genome location (synteny) (1)
    Download Curated Orthology
    CITATIONS (36)