Research
General Information
ZIRC
ZFIN ID: ZDB-GENE-040611-2
Gene Name: neuropilin 2a
Gene Symbol: nrp2a
Previous Name: npn-2A (1)
Location: Chr: 1   Details
Nomenclature History
GENE EXPRESSION
All Expression Data: 11 figures from 10 publications
Wild-type Stages, Structures: Segmentation:1-4 somites (10.33h-11.66h) to Larval:Day 5 (120.0h-144.0h, 3.9mm, 6 teeth)
  brain, cranial neural crest cell, hindbrain, posterior cardinal vein (all 8) expand
MUTANTS AND TARGETED KNOCKDOWNS
Alleles: la021215Tg, sa13255, sa13721
Knockdown reagents: MO1-nrp2a (1), MO2-nrp2a (1), MO3-nrp2a (1), MO4-nrp2a (1)
PHENOTYPE
Data: Fig. 6 from Hermans et al., 2010
Observed in: lymphangioblast cord, thoracic duct, vascular lymphangioblast
GENE ONTOLOGY
Ontology GO Term
Biological Process neural crest cell migration (more)
Cellular Component membrane (more)
Molecular Function metal ion binding (more)
GO Terms (all 10)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000421 (1)
  • InterPro:IPR000859 (1)
  • InterPro:IPR000998 (1)
  • InterPro:IPR008979 (1)
  • InterPro:IPR008985 (1)
  • InterPro:IPR014648 (1)
  • InterPro:IPR022579 (1)
  • PROSITE:PS01180 (1)
  • PROSITE:PS01285 (1)
  • PROSITE:PS01286 (1)
  • PROSITE:PS50022 (1)
  • PROSITE:PS50060 (1)
  • Pfam:PF00431 (1)
  • Pfam:PF00629 (1)
  • Pfam:PF00754 (1)
  • Pfam:PF11980 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA nrp2a-001 (1) 2882
    nrp2a-002 (1) 353
     Withdrawn Transcriptsextinct
    GENE PRODUCT DESCRIPTION
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM nrp2a No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    nrp2a Contained in: [BAC] CH73-76B22 (1) (order this)
    [Fosmid] CH1073-331F6 (1) (order this), CH1073-435A3 (1) (order this)
    nrp2a Encodes: [cDNA] MGC:193601 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_212965 (1) 5316 bp
    Genomic GenBank:CU469569 (1) 102276 bp
    Select Tool
    Polypeptide UniProtKB:B3DFP6 (1) 927 aa
    Sequence Clusters UniGene:29401 (1)
    Sequence Information (all 33)
    OTHER nrp2a GENE PAGES
  • Gene:405901 (1)
  • VEGA:OTTDARG00000037671 (1)
  • Ensembl(Zv9):ENSDARG00000031622 (1)
  • ORTHOLOGY
      Evidence
    Species Symbol Chr (Position) Accession # AA CL
    Zebrafish nrp2a 1  
    Human NRP2 2 (2q33.3)
  • OMIM:602070
  • Gene:8828
  • Mouse Nrp2 1 ( 31.35 cM)
  • MGI:1100492
  • Gene:18187
  • Orthology Details
    CITATIONS (32)