ZFIN ID: ZDB-GENE-030616-132
Gene Name: MYC binding protein 2
Gene Symbol: mycbp2
Previous Names: esr, esrom (2), fa97c06, ns:zft368, PAM (1), si:busm1-12g7.1, si:dz12g7.1, si:dz256p4.1, til, tilsit, wu:fa97c06, xx:zft368, zft368
Location: Chr: 9 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 3 figures from 3 publications
Wild-type Stages, Structures: Cleavage:4-cell (1.0h-1.25h) to Adult (90d-730d, breeding adult)
  brain, eye, gill, heart (all 11) expand
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS 
Allele Type Mutagen Suppliers
la016495Tg Transgenic Insertion DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la016496Tg Transgenic Insertion DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • mycbp2_unspecified Unspecified
    sa17311 Point Mutation ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • sa21455 Point Mutation ENU
    tb241a Unknown ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • te250 Small Deletion ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • te275 Insertion ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • te279 Unknown ENU
    te376 Unknown ENU
    tf4z Unknown ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • tg5 Unknown ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • tg06a Unknown ENU
    tg265a Unknown ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • th36b Unknown ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • th222 Unknown ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • tj236 Unknown ENU
    tn207b Point Mutation ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • tp203 Point Mutation ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • tq213c Unknown ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • ts208 Unknown ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • ty130b Point Mutation ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Targeting reagents: MO1-mycbp2 (1), MO2-mycbp2 (1)
    PHENOTYPE
    Data: 25 figures from 6 publications
    Observed in: developmental pigmentation, eye ipsilateral side, habenular commissure, nervous system (all 12) expand
    DISEASE ASSOCIATED WITH mycbp2 HUMAN ORTHOLOG No data available
    GENE ONTOLOGY 
    Ontology GO Term
    Biological Process axon choice point recognition (more)
    Cellular Component cytoplasm (more)
    Molecular Function ubiquitin-protein transferase activity (more)
    GO Terms (all 11)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000408 (1)
  • InterPro:IPR001841 (1)
  • InterPro:IPR003646 (1)
  • InterPro:IPR004939 (1)
  • InterPro:IPR008979 (1)
  • InterPro:IPR009091 (1)
  • InterPro:IPR012983 (1)
  • InterPro:IPR013083 (1)
  • InterPro:IPR013783 (1)
  • InterPro:IPR014756 (1)
  • InterPro:IPR017868 (1)
  • PROSITE:PS00626 (1)
  • PROSITE:PS50012 (1)
  • PROSITE:PS50089 (1)
  • PROSITE:PS50194 (1)
  • PROSITE:PS51284 (1)
  • Pfam:PF00415 (1)
  • Pfam:PF00630 (1)
  • Pfam:PF08005 (1)
  • Pfam:PF08239 (1)
  • Pfam:PF13639 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA mycbp2-001 (1) 15337
    ottdart00000001875 (1) 2743
    ottdart00000001995 (1) 9225
    GENE PRODUCT DESCRIPTION
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM mycbp2 No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS 
    mycbp2Contained in: [BAC] CH211-4P8 (1) (order this), CH211-221B16 (1) (order this), CH211-279B21 (1) (order this), DKEY-250A21 (1) (order this)
    [PAC] BUSM1-12G7 (1) (order this), BUSM1-256P4 (order this)
    mycbp2Encodes: [EST] fa97c06, zft368
    SEQUENCE INFORMATION 
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001012247 (1) 15334bp
    Genomic GenBank:AL954845 (1) 226343bp Blast at MegaBLAST
    Polypeptide UniProtKB:F1QI76 (1) 4736aa
    Sequence Clusters UniGene:146702 (1)
    Sequence Information (all 67)
    OTHER mycbp2 GENE PAGES 
  • Gene:368439 (1)
  • VEGA:OTTDARG00000001756 (1)
  • VEGA:OTTDARG00000001868 (1)
  • VEGA:OTTDARG00000030613 (1)
  • Ensembl(GRCz10):ENSDARG00000001220 (1)
  • ORTHOLOGY for mycbp2 (Chr: 9) 
    Species Symbol Chromosome Accession # Evidence
    Human MYCBP2 13
  • Gene:23077
  • OMIM:610392
  • HGNC:23386
  • Amino acid sequence comparison (4)
    Conserved genome location (synteny) (1)
    Mouse Mycbp2 14
  • MGI:2179432
  • Gene:105689
  • Amino acid sequence comparison (2)
    Conserved genome location (synteny) (1)
    Download Curated Orthology
    CITATIONS (33)