Research
General Information
ZIRC
ZFIN ID: ZDB-GENE-030131-3232
Gene Name: histone deacetylase 6
Gene Symbol: hdac6
Previous Name: wu:fc31d02
Location: Chr: 8   Details
Nomenclature History
GENE EXPRESSION
Curated Microarray Expression: GEO (1)
MUTANTS AND TARGETED KNOCKDOWNS
Alleles: la026686Tg, sa18529
Knockdown reagents: MO1-hdac6 (1), MO2-hdac6 (1)
PHENOTYPE
Data: Fig. 2 from Kaluza et al., 2011
Observed in: dorsal longitudinal anastomotic vessel, intersegmental vessel

Phenotype of Human Orthologue OMIM Phenotype ID
Chondrodysplasia with platyspondyly, distinctive brachydactyly, hydrocephaly, and microphthalmia 300863
GENE ONTOLOGY
Ontology GO Term
Biological Process angiogenesis (more)
Molecular Function hydrolase activity (more)
GO Terms (all 4)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000286 (1)
  • InterPro:IPR001607 (1)
  • InterPro:IPR013083 (1)
  • InterPro:IPR023801 (1)
  • PROSITE:PS50271 (1)
  • Pfam:PF00850 (1)
  • Pfam:PF02148 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA hdac6-001 (1) 3951
    hdac6-002 (1) 418
    GENE PRODUCT DESCRIPTION
    ANTIBODIES No data available
    CONSTRUCTS WITH SEQUENCES FROM hdac6 No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    hdac6 Contained in: [BAC] CH211-150E8 (1) (order this)
    hdac6 Contains: [SNP] rs3728138 (1), rs3728139 (1), rs3728140 (1)
    hdac6 Encodes: [EST] fc31d02
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:XM_688766 (1) 4888 bp
    Genomic GenBank:BX469901 (1) 180553 bp
    Select Tool
    Polypeptide UniProtKB:F8W4B7 (1) 1081 aa
    Sequence Clusters UniGene:78784 (1)
    Sequence Information (all 14)
    OTHER hdac6 GENE PAGES
  • Gene:565482 (1)
  • VEGA:OTTDARG00000034603 (1)
  • Ensembl(Zv9):ENSDARG00000008384 (1)
  • ORTHOLOGY
      Evidence
    Species Symbol Chr (Position) Accession # AA
    Zebrafish hdac6 8  
    Human HDAC6 X (Xp11.23)
  • OMIM:300272
  • Gene:10013
  • Orthology Details
    CITATIONS (16)