ZFIN ID: ZDB-GENE-030123-1
Gene Name: ttk protein kinase
Gene Symbol: ttk
Previous Names: mps1, ncp (1), nightcap (1)
Location: Chr: 16   Details
Nomenclature History
GENE EXPRESSION
All Expression Data: 13 figures from 6 publications
Directly Submitted Expression Data: 7 figures (7 images) from Thisse et al., 2004 [MGC:64151]
Wild-type Stages, Structures: Gastrula:50%-epiboly (5.25h-5.66h) to Adult (90d-730d, breeding adult)
  caudal fin, proliferative region, unspecified
Curated Microarray Expression: GEO (1)
MUTANTS AND TARGETED KNOCKDOWNS
Mutant lines: 3 Genotypes

Allele Type Mutagen Suppliers
hi1830Tg Transgenic Insertion DNA
sa11341 Point Mutation ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • European Zebrafish Resource Center (EZRC) (order this)
  • sa18112 Point Mutation ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • zp1 Point Mutation ENU
    PHENOTYPE
    Data: 2 figures from Phenotype Annotation (1994-2006)
    Observed in: eye, gut, liver, nervous system (all 5) expand
    DISEASE ASSOCIATED WITH ttk HUMAN ORTHOLOG No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process anatomical structure homeostasis (more)
    Molecular Function ATP binding (more)
    GO Terms (all 19)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000719 (1)
  • InterPro:IPR002290 (1)
  • InterPro:IPR008271 (1)
  • InterPro:IPR011009 (1)
  • InterPro:IPR011990 (1)
  • InterPro:IPR017441 (1)
  • InterPro:IPR027084 (1)
  • PROSITE:PS00107 (1)
  • PROSITE:PS00108 (1)
  • PROSITE:PS50011 (1)
  • Pfam:PF00069 (1)
  • EC:2.7.12.1 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA ttk-001 (1) 3323
    ttk-002 (1) 3182
    ttk-003 (1) 698
    GENE PRODUCT DESCRIPTION
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM ttk No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    ttk Contained in: [Fosmid] CH1073-438L20 (1) (order this)
    ttk Encodes: [cDNA] MGC:64151 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_175042 (1) 3183 bp
    Genomic GenBank:CU694364 (1) 41710 bp
    Select Tool
    Polypeptide UniProtKB:E9QBU7 (1) 983 aa
    Sequence Clusters UniGene:80755 (1)
    Sequence Information (all 19)
    OTHER ttk GENE PAGES
  • Gene:317763 (1)
  • VEGA:OTTDARG00000033096 (1)
  • Ensembl(Zv9):ENSDARG00000041361 (1)
  • ORTHOLOGY
      Evidence
    Species Symbol Chr (Position) Accession # AA CL
    Zebrafish ttk 16  
    Human TTK 6 (6q14.1)
  • OMIM:604092
  • Gene:7272
  • Mouse Ttk 9 ( 45.61 cM)
  • MGI:1194921
  • Gene:22137
  • Orthology Details
    CITATIONS (34)