Research
General Information
ZIRC
ZFIN ID: ZDB-GENE-030123-1
Gene Name: ttk protein kinase
Gene Symbol: ttk
Previous Names: mps1, ncp (1), nightcap (1)
Location: Chr: 16   Details
Nomenclature History
GENE EXPRESSION
All Expression Data: 12 figures from 5 publications
Directly Submitted Expression Data: 7 figures (7 images) from Thisse et al., 2004 [MGC:64151]
Wild-type Stages, Structures: Gastrula:50%-epiboly (5.25h-5.66h) to Adult (90d-730d, breeding adult)
  caudal fin, proliferative region, unspecified
Curated Microarray Expression: GEO (1)
MUTANTS AND TARGETED KNOCKDOWNS
Mutant lines: 3 genotypes
Alleles: hi1830Tg, sa11341, sa18112, zp1
PHENOTYPE
Data: 2 figures from Phenotype Annotation (1994-2006)
Observed in: eye, gut, liver, nervous system (all 5) expand
GENE ONTOLOGY
Ontology GO Term
Biological Process anatomical structure homeostasis (more)
Molecular Function ATP binding (more)
GO Terms (all 21)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000719 (1)
  • InterPro:IPR002290 (1)
  • InterPro:IPR008271 (1)
  • InterPro:IPR011009 (1)
  • InterPro:IPR011990 (1)
  • InterPro:IPR017441 (1)
  • InterPro:IPR027084 (1)
  • PROSITE:PS00107 (1)
  • PROSITE:PS00108 (1)
  • PROSITE:PS50011 (1)
  • Pfam:PF00069 (1)
  • EC:2.7.12.1 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA ttk-001 (1) 3323
    ttk-002 (1) 3182
    ttk-003 (1) 698
    GENE PRODUCT DESCRIPTION
    ANTIBODIES No data available
    CONSTRUCTS WITH SEQUENCES FROM ttk No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    ttk Contained in: [Fosmid] CH1073-438L20 (1) (order this)
    ttk Encodes: [cDNA] MGC:64151 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_175042 (1) 3183 bp
    Genomic GenBank:CU694364 (1) 41710 bp
    Select Tool
    Polypeptide UniProtKB:E9QBU7 (1) 983 aa
    Sequence Clusters UniGene:80755 (1)
    Sequence Information (all 19)
    OTHER ttk GENE PAGES
  • Gene:317763 (1)
  • VEGA:OTTDARG00000033096 (1)
  • Ensembl(Zv9):ENSDARG00000041361 (1)
  • ORTHOLOGY
      Evidence
    Species Symbol Chr (Position) Accession # AA CL
    Zebrafish ttk 16  
    Human TTK 6 (6q14.1)
  • OMIM:604092
  • Gene:7272
  • Mouse Ttk 9 ( 45.61 cM)
  • MGI:1194921
  • Gene:22137
  • Orthology Details
    CITATIONS (34)