ZFIN ID: ZDB-GENE-990615-5
Gene Name: T-box 16
Gene Symbol: tbx16
GO Details
Ontology Qualifier Term Evidence Inferred From Annotation Extension Reference(s)
Molecular Function DNA binding IDA Garnett et al., 2009
DNA binding IEA UniProtKB-KW:KW-0238 ZFIN Electronic Annotation
DNA-binding transcription factor activity IEA InterPro:IPR001699 ZFIN Electronic Annotation
DNA-binding transcription factor activity IEA InterPro:IPR008967 ZFIN Electronic Annotation
DNA-binding transcription factor activity IEA InterPro:IPR018186 ZFIN Electronic Annotation
DNA-binding transcription factor activity IEA InterPro:IPR036960 ZFIN Electronic Annotation
transcription regulatory region DNA binding IDA Garnett et al., 2009
Cellular Component nuclear chromatin IDA Nelson et al., 2017
nucleus IDA Amacher et al., 2002
nucleus IEA InterPro:IPR001699 ZFIN Electronic Annotation
nucleus IEA InterPro:IPR018186 ZFIN Electronic Annotation
nucleus IEA InterPro:IPR036960 ZFIN Electronic Annotation
nucleus IEA UniProtKB-KW:KW-0539 ZFIN Electronic Annotation
Biological Process angiogenesis IMP tbx16hi3714Tg/hi3714Tg Burns et al., 2009
convergent extension involved in axis elongation IMP tbx16b104/b104 (AB) Hammerschmidt et al., 1996
convergent extension involved in nephron morphogenesis IMP tbx16b104/b104 Huang et al., 2013
determination of left/right symmetry IMP MO3-tbx16 Amack et al., 2007
determination of left/right symmetry IMP tbx16tm41/tm41 Chen et al., 1997
determination of left/right symmetry IMP tbx16b104/b104 (AB) Amack et al., 2007
digestive tract development IGI tbxta Nelson et al., 2017
embryonic heart tube morphogenesis IMP tbx16tm41/tm41 Chen et al., 1997
erythrocyte development IMP tbx16b104/b104 Warga et al., 2013
erythrocyte differentiation IMP tbx16b104/b104 (AB) Rohde et al., 2004
heart looping IMP tbx16tm41/tm41 Chen et al., 1997
hematopoietic stem cell differentiation IMP MO4-tbx16 Burns et al., 2009
hematopoietic stem cell differentiation IMP tbx16hi3714Tg/hi3714Tg Burns et al., 2009
intermediate mesoderm development IMP tbx16b104/b104 (AB) Hogan et al., 2006
Kupffer's vesicle development IGI MO3-tbx16, MO5-sdc2 Arrington et al., 2013
Kupffer's vesicle development IGI MO3-tbx16, MO1-fgf2 Arrington et al., 2013
liver development IGI tbxta Nelson et al., 2017
mesoderm development IGI MO1-tbx16, MO2-tbx16, tbxtab195/b195 Honjo et al., 2005
mesoderm development IGI MO1-msgn1, tbx16kt378b/kt378b Yabe et al., 2012
mesoderm development IGI tbxtab195/b195; tbx16b104/b104 Amacher et al., 2002
mesodermal to mesenchymal transition involved in gastrulation IMP MO1-tbx16, MO2-tbx16 Row et al., 2011
myeloid cell development IMP tbx16b104/b104 Warga et al., 2013
pancreas development IGI tbxta Nelson et al., 2017
paraxial mesoderm formation IGI tbx16lz35/z35; tbx16b104/b104 Morrow et al., 2017
pronephric duct morphogenesis IMP MO4-tbx16 Wingert et al., 2011
pronephric glomerulus morphogenesis IMP tbx16b104/b104 Huang et al., 2013
pronephros development IMP tbx16b104/b104 Warga et al., 2013
regulation of BMP signaling pathway involved in heart jogging IMP tbx16tm41/tm41 Chen et al., 1997
regulation of endodermal cell fate specification IGI tbxta Nelson et al., 2017
regulation of transcription, DNA-templated IEA InterPro:IPR001699 ZFIN Electronic Annotation
regulation of transcription, DNA-templated IEA InterPro:IPR008967 ZFIN Electronic Annotation
regulation of transcription, DNA-templated IEA InterPro:IPR018186 ZFIN Electronic Annotation
regulation of transcription, DNA-templated IEA InterPro:IPR036960 ZFIN Electronic Annotation
somatic muscle development IMP tbx16kt378b/kt378b Yabe et al., 2012
somite development IGI tbx16lz35/z35; tbx16b104/b104 Morrow et al., 2017
somitogenesis IGI tbx16b104/b104; chrdks1/ks1 O'Neill et al., 2013
somitogenesis IMP tbx16b104/b104 O'Neill et al., 2013
vasculogenesis IMP tbx16hi3714Tg/hi3714Tg Burns et al., 2009