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General Information
ZIRC
ZFIN ID: ZDB-GENE-990415-94
Gene Name: heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 1
Gene Symbol: hsp90aa1.1
GO Details
Ontology Qualifier Term Evidence Inferred From Annotation Extension Reference(s)
Molecular Function ATP binding IBA RGD:631409, PANTHER:PTN000163632, UniProtKB:P07900 Gaudet et al., 2010
ATP binding IEA InterPro:IPR001404 ZFIN Electronic Annotation
ATP binding IEA InterPro:IPR019805 ZFIN Electronic Annotation
ATP binding IEA UniProtKB-KW:KW-0067 ZFIN Electronic Annotation
ATP binding ISS UniProtKB:P07900 GOA et al., 2007
ATPase activity ISS UniProtKB:P07900 GOA et al., 2007
disordered domain specific binding IBA PANTHER:PTN000163632, UniProtKB:Q76LV2, UniProtKB:P07900 Gaudet et al., 2010
nitric-oxide synthase regulator activity ISS UniProtKB:P07901 GOA et al., 2007
nucleotide binding IEA UniProtKB-KW:KW-0547 ZFIN Electronic Annotation
protein binding IPI UniProtKB:Q8UVX6 Etard et al., 2007
unfolded protein binding IBA SGD:S000006161, PANTHER:PTN000163527, PomBase:SPAC926.04c, SGD:S000004798, FB:FBgn0001233 Gaudet et al., 2010
unfolded protein binding IEA InterPro:IPR001404 ZFIN Electronic Annotation
unfolded protein binding IEA InterPro:IPR019805 ZFIN Electronic Annotation
Cellular Component A band IEA UniProtKB-SubCell:SL-0476 UniProt-GOA
cell surface IBA RGD:631409, RGD:1303075, CGD:CAL0000201062, PANTHER:PTN000163629, UniProtKB:P11501 Gaudet et al., 2010
cytoplasm IBA TAIR:locus:2161790, CGD:CAL0000201062, UniProtKB:A0A1D5PUL6, FB:FBgn0001233, UniProtKB:Q76LV2, TAIR:locus:2161775, PANTHER:PTN000163629, UniProtKB:P11501, MGI:MGI:96247, SGD:S000006161, RGD:631409, MGI:MGI:96250, RGD:1303075, UniProtKB:P08238, WB:WBGene00000915, dictyBase:DDB_G0267400, UniProtKB:P07900 Gaudet et al., 2010
cytoplasm IEA UniProtKB-KW:KW-0963 ZFIN Electronic Annotation
cytosol IBA RGD:631409, MGI:MGI:96250, RGD:1303075, UniProtKB:P08238, UniProtKB:A0A1D5PUL6, dictyBase:DDB_G0267400, TAIR:locus:2161775, PANTHER:PTN000163629, UniProtKB:P11501 Gaudet et al., 2010
melanosome IEA UniProtKB-SubCell:SL-0161 UniProt-GOA
myelin sheath IBA RGD:631409, PANTHER:PTN002609464 Gaudet et al., 2010
neuronal cell body IBA RGD:631409, PANTHER:PTN002609464, MGI:MGI:96250, UniProtKB:P11501 Gaudet et al., 2010
nucleus IBA PANTHER:PTN002609464, MGI:MGI:96250, UniProtKB:P11501 Gaudet et al., 2010
perinuclear region of cytoplasm IBA RGD:631409, MGI:MGI:96250, WB:WBGene00000915, FB:FBgn0001233, PANTHER:PTN000163629, MGI:MGI:96247 Gaudet et al., 2010
plasma membrane IBA RGD:631409, TAIR:locus:2161790, MGI:MGI:96250, CGD:CAL0000201062, PANTHER:PTN000163629, TAIR:locus:2161775, UniProtKB:P11501 Gaudet et al., 2010
protein-containing complex IBA RGD:631409, MGI:MGI:96250, UniProtKB:P08238, WB:WBGene00000915, PANTHER:PTN000163629, MGI:MGI:96247, UniProtKB:P07900, UniProtKB:P11501 Gaudet et al., 2010
Z disc IDA Etard et al., 2008
Biological Process cellular response to heat IBA SGD:S000004798, MGI:MGI:96250, CGD:CAL0000201062, PANTHER:PTN000163629, MGI:MGI:96247 Gaudet et al., 2010
leukocyte migration IMP MO1-hsp90aa1.1 Ye et al., 2015
muscle organ development IEA UniProtKB-KW:KW-0517 ZFIN Electronic Annotation
myofibril assembly IMP MO2-hsp90aa1.1 Etard et al., 2007
positive regulation of nitric oxide biosynthetic process ISS UniProtKB:P07901 GOA et al., 2007
protein folding IBA SGD:S000006161, PANTHER:PTN000163527, PomBase:SPAC926.04c, SGD:S000004798, MGI:MGI:96250, CGD:CAL0000201062, WB:WBGene00000915, UniProtKB:P0A6Z3, MGI:MGI:96247 Gaudet et al., 2010
protein folding IEA InterPro:IPR001404 ZFIN Electronic Annotation
protein folding IEA InterPro:IPR019805 ZFIN Electronic Annotation
protein stabilization IBA PANTHER:PTN000163629, UniProtKB:P11501, UniProtKB:P07900 Gaudet et al., 2010
response to metal ion IDA Redelstein et al., 2015
sarcomerogenesis IMP hsp90aa1.1u45/u45 Hawkins et al., 2008
skeletal muscle myosin thick filament assembly IMP hsp90aa1.1u45/u45 Hawkins et al., 2008
skeletal muscle thin filament assembly IMP hsp90aa1.1tu44c/tu44c Codina et al., 2010
skeletal myofibril assembly IMP MO4-hsp90aa1.1 Du et al., 2008
striated muscle myosin thick filament assembly IMP hsp90aa1.1tu44c/tu44c Codina et al., 2010