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General Information
ZIRC
ZFIN ID: ZDB-GENE-990415-44
Gene Name: cytochrome P450, family 26, subfamily A, polypeptide 1
Gene Symbol: cyp26a1
GO Details
Ontology Qualifier Term Evidence Inferred From Annotation Extension Reference(s)
Molecular Function C-22 sterol desaturase activity IBA PANTHER:PTN000669384, SGD:S000004617 Gaudet et al., 2010
heme binding IEA InterPro:IPR001128 ZFIN Electronic Annotation
heme binding IEA InterPro:IPR002401 ZFIN Electronic Annotation
heme binding IEA InterPro:IPR036396 ZFIN Electronic Annotation
iron ion binding IEA InterPro:IPR001128 ZFIN Electronic Annotation
iron ion binding IEA InterPro:IPR002401 ZFIN Electronic Annotation
iron ion binding IEA InterPro:IPR036396 ZFIN Electronic Annotation
metal ion binding IEA UniProtKB-KW:KW-0479 ZFIN Electronic Annotation
monooxygenase activity IBA UniProtKB:Q8GSQ1, MGI:MGI:1096359, UniProtKB:Q9NR63, UniProtKB:Q2MJ20, UniProtKB:Q6V0L0, TAIR:locus:2152292, UniProtKB:F6H9N6, RGD:631379, UniProtKB:Q5CCK3, UniProtKB:Q8L7D5, TAIR:locus:2091571, TAIR:locus:2098802, TAIR:locus:2158916, TAIR:locus:2158961, UniProtKB:Q9PUB4, TAIR:locus:2115220, PANTHER:PTN000669383, UniProtKB:O43174 Gaudet et al., 2010
monooxygenase activity IEA UniProtKB-KW:KW-0503 ZFIN Electronic Annotation
oxidoreductase activity IBA UniProtKB:Q8GSQ1, PANTHER:PTN001209376, TAIR:locus:2098802, TAIR:locus:2152292, UniProtKB:Q5CCK3 Gaudet et al., 2010
oxidoreductase activity IEA UniProtKB-KW:KW-0560 ZFIN Electronic Annotation
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen IEA InterPro:IPR001128 ZFIN Electronic Annotation
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen IEA InterPro:IPR002401 ZFIN Electronic Annotation
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen IEA InterPro:IPR017972 ZFIN Electronic Annotation
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen IEA InterPro:IPR036396 ZFIN Electronic Annotation
retinoic acid 4-hydroxylase activity IDA White et al., 1996
Cellular Component endoplasmic reticulum IEA UniProtKB-KW:KW-0256 ZFIN Electronic Annotation
endoplasmic reticulum membrane IEA UniProtKB-SubCell:SL-0097 UniProt-GOA
integral component of membrane IEA UniProtKB-KW:KW-0812 ZFIN Electronic Annotation
intracellular membrane-bounded organelle IEA UniProtKB-KW:KW-0492 ZFIN Electronic Annotation
membrane IEA UniProtKB-KW:KW-0472 ZFIN Electronic Annotation
Biological Process anterior/posterior pattern specification involved in pronephros development IMP MO1-cyp26a1 Naylor et al., 2016
atrial cardiac muscle cell development IGI MO1-cyp26c1, cyp26a1rw716/rw716 Rydeen et al., 2014
atrial cardiac muscle cell development IGI MO4-cyp26a1, MO1-cyp26c1, MO5-cyp26a1 Rydeen et al., 2014
blood vessel development IMP MO1-cyp26a1 Emoto et al., 2005
blood vessel development IMP cyp26a1rw716/rw716 Emoto et al., 2005
brain morphogenesis IMP cyp26a1rw716/rw716 Gongal et al., 2008
cellular response to vitamin A IDA Moise et al., 2007
ergosterol biosynthetic process IBA PANTHER:PTN000669384, SGD:S000004617, PomBase:SPAC19A8.04 Gaudet et al., 2010
forebrain anterior/posterior pattern specification IGI MO1-tgif1, cyp26a1 Gongal et al., 2008
heart development IGI MO4-cyp26a1, MO5-cyp26a1, MO2-rarab D'Aniello et al., 2013
heart development IMP MO4-cyp26a1, MO5-cyp26a1 D'Aniello et al., 2013
hindbrain development IGI MO1-cyp26c1, MO1-cyp26b1, cyp26a1rw716/rw716 Hernandez et al., 2007
hindbrain development IMP cyp26a1rw716/rw716 Emoto et al., 2005
mesodermal-endodermal cell signaling IMP cyp26a1rw716/rw716 Kinkel et al., 2009
midbrain-hindbrain boundary development IGI MO4-cyp26a1, MO5-cyp26a1, MO2-rarab D'Aniello et al., 2013
outflow tract morphogenesis IGI MO4-cyp26a1, MO1-cyp26c1 Rydeen et al., 2016
oxidation-reduction process IBA TAIR:locus:2040939, PANTHER:PTN001209376, TAIR:locus:2040929, TAIR:locus:2098802, UniProtKB:Q9NR63, TAIR:locus:2094058, UniProtKB:Q6V0L0 Gaudet et al., 2010
oxidation-reduction process IEA InterPro:IPR001128 ZFIN Electronic Annotation
oxidation-reduction process IEA InterPro:IPR002401 ZFIN Electronic Annotation
oxidation-reduction process IEA InterPro:IPR017972 ZFIN Electronic Annotation
oxidation-reduction process IEA InterPro:IPR036396 ZFIN Electronic Annotation
oxidation-reduction process IEA UniProtKB-KW:KW-0560 ZFIN Electronic Annotation
pancreas development IGI MO1-cyp26c1, MO1-cyp26b1, cyp26a1rw716/rw716 Kinkel et al., 2009
pancreas development IMP cyp26a1rw716/rw716 Kinkel et al., 2009
retinal metabolic process IMP cyp26a1rw716/rw716 Hernandez et al., 2007
retinoic acid catabolic process IMP Kinkel et al., 2009
retinoic acid metabolic process IDA 2 Publications
retinoic acid metabolic process IMP cyp26a1rw716/rw716 Hernandez et al., 2007
retinoic acid receptor signaling pathway involved in somitogenesis IMP MO1-mir19 Franzosa et al., 2013
rhombomere 4 morphogenesis IGI MO1-cyp26b1, cyp26a1rw716/rw716 Hernandez et al., 2007
rhombomere 4 morphogenesis IGI MO1-cyp26c1, MO1-cyp26b1, cyp26a1rw716/rw716 Hernandez et al., 2007
rhombomere 4 morphogenesis IGI MO1-cyp26c1, cyp26a1rw716/rw716 Hernandez et al., 2007
rhombomere 4 morphogenesis IMP cyp26a1rw716/rw716 Hernandez et al., 2007
somitogenesis IMP MO1-cyp26a1 Echeverri et al., 2007
sterol metabolic process IBA PANTHER:PTN001209376, UniProtKB:P9WPP9, TAIR:locus:2027312 Gaudet et al., 2010
vasculature development IGI MO1-cyp26c1, MO4-cyp26a1, MO5-cyp26a1 Rydeen et al., 2014
vasculature development IGI MO1-cyp26c1, cyp26a1rw716/rw716 Rydeen et al., 2014