ZFIN ID: ZDB-GENE-990415-234
Gene Name: recombination activating 1
Gene Symbol: rag1
GO Details
Ontology Qualifier Term Evidence Inferred From Annotation Extension Reference(s)
Molecular Function catalytic activity IEA UniProtKB-KW:KW-0511 ZFIN Electronic Annotation
DNA binding IEA UniProtKB-KW:KW-0238 ZFIN Electronic Annotation
CONTRIBUTES TO double-stranded DNA endodeoxyribonuclease activity IPI rag2 Ru et al., 2018
endonuclease activity IEA InterPro:IPR024627 ZFIN Electronic Annotation
endonuclease activity IEA UniProtKB-KW:KW-0255 ZFIN Electronic Annotation
endonuclease activity ISS UniProtKB:P15919 GOA et al., 2007
histone binding ISS UniProtKB:P15919 GOA et al., 2007
hydrolase activity IEA UniProtKB-KW:KW-0378 ZFIN Electronic Annotation
magnesium ion binding IDA Ru et al., 2015
metal ion binding IEA InterPro:IPR018957 ZFIN Electronic Annotation
metal ion binding IEA UniProtKB-KW:KW-0479 ZFIN Electronic Annotation
nuclease activity IEA UniProtKB-KW:KW-0540 ZFIN Electronic Annotation
protein binding IPI rag2, rag1 Ru et al., 2015
protein homodimerization activity IEA UniRule:UR000413279 UniProt curators
protein homodimerization activity ISS UniProtKB:P15919 GOA et al., 2007
sequence-specific DNA binding IEA UniRule:UR000400411 UniProt curators
sequence-specific DNA binding IEA InterPro:IPR024627 ZFIN Electronic Annotation
sequence-specific DNA binding IPI rag2, rag1 Ru et al., 2015
sequence-specific DNA binding ISS UniProtKB:P15919 GOA et al., 2007
transferase activity IEA UniProtKB-KW:KW-0808 ZFIN Electronic Annotation
ubiquitin protein ligase activity IEA InterPro:IPR024627 ZFIN Electronic Annotation
ubiquitin-protein transferase activity ISS UniProtKB:P15919 GOA et al., 2007
zinc ion binding ISS UniProtKB:P15919 GOA et al., 2007
Cellular Component DNA recombinase complex IPI rag2, rag1 Ru et al., 2015
endodeoxyribonuclease complex IPI rag2 Ru et al., 2018
nucleus IEA UniProtKB-KW:KW-0539 ZFIN Electronic Annotation
nucleus IEA UniProtKB-SubCell:SL-0191 UniProt-GOA
nucleus ISS UniProtKB:P15919 GOA et al., 2007
Biological Process B cell differentiation ISS UniProtKB:P15919 GOA et al., 2007
chromatin organization IEA UniProtKB-KW:KW-0156 ZFIN Electronic Annotation
DNA recombination IEA UniProtKB-KW:KW-0233 ZFIN Electronic Annotation
histone monoubiquitination ISS UniProtKB:P15919 GOA et al., 2007
metabolic process IEA UniProtKB-KW:KW-0511 ZFIN Electronic Annotation
protein-DNA complex assembly IPI rag2, rag1 Ru et al., 2015
somatic diversification of immune receptors via germline recombination within a single locus IMP rag1t26683/t26683 Tokunaga et al., 2017
T cell differentiation in thymus ISS UniProtKB:P15919 GOA et al., 2007
V(D)J recombination IEA UniRule:UR000400411 UniProt curators
V(D)J recombination IEA InterPro:IPR024627 ZFIN Electronic Annotation
V(D)J recombination IPI rag2 Ru et al., 2018
V(D)J recombination IPI rag2, rag1 Ru et al., 2015
V(D)J recombination ISS UniProtKB:P15919 GOA et al., 2007