Gene

pax7a

ID
ZDB-GENE-990415-201
Name
paired box 7a
Symbol
pax7a Nomenclature History
Previous Names
  • pax7 (1)
  • pax7c (1)
  • pax7d (1)
  • pax7e (1)
Type
protein_coding_gene
Location
Chr: 11 Mapping Details/Browsers
Description
Predicted to have sequence-specific DNA binding activity. Involved in developmental pigmentation; regulation of xanthophore differentiation; and wound healing. Localizes to nucleus. Human ortholog(s) of this gene implicated in alveolar rhabdomyosarcoma. Is expressed in several structures, including central nervous system; muscle; neural crest; neural tube; and post-vent region. Orthologous to human PAX7 (paired box 7).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
62 figures from 41 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
2 figures from 2 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With pax7a Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
alveolar rhabdomyosarcoma Alliance Rhabdomyosarcoma 2, alveolar 268220
congenital myopathy 19 Alliance Congenital myopathy 19 618578
Associated With pax7a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR017970 Homeobox, conserved site
Domain IPR001356 Homeobox domain
Domain IPR001523 Paired domain
Domain IPR003654 OAR domain
Domain IPR022106 Paired box protein 7, C-terminal
Domain IPR043182 Paired DNA-binding domain
Family IPR043565 PAX family
Homologous_superfamily IPR009057 Homeobox-like domain superfamily
Homologous_superfamily IPR036388 Winged helix-like DNA-binding domain superfamily
Domain Details Per Protein
Protein Length Homeobox, conserved site Homeobox domain Homeobox-like domain superfamily OAR domain Paired box protein 7, C-terminal Paired DNA-binding domain Paired domain PAX family Winged helix-like DNA-binding domain superfamily
UniProtKB:A0A0R4IM38 487
UniProtKB:O57418 507
UniProtKB:A0A8M3B4A0 502
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations