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General Information
ZIRC
ZFIN ID: ZDB-GENE-980526-44
Gene Name: patched 2
Gene Symbol: ptch2
GO Details
Ontology Qualifier Term Evidence Inferred From Annotation Extension Reference(s)
Molecular Function hedgehog family protein binding IBA UniProtKB:Q13635, PANTHER:PTN000847539, UniProtKB:Q9Y6C5 Gaudet et al., 2010
hedgehog receptor activity IBA FB:FBgn0003892, PANTHER:PTN000847539 Gaudet et al., 2010
hedgehog receptor activity IEA InterPro:IPR004766 ZFIN Electronic Annotation
smoothened binding IBA UniProtKB:Q13635, PANTHER:PTN000847539, UniProtKB:Q9Y6C5 Gaudet et al., 2010
Cellular Component integral component of membrane IEA InterPro:IPR003392 ZFIN Electronic Annotation
integral component of membrane IEA InterPro:IPR004766 ZFIN Electronic Annotation
integral component of membrane IEA UniProtKB-KW:KW-0812 ZFIN Electronic Annotation
membrane IEA UniProtKB-KW:KW-0472 ZFIN Electronic Annotation
plasma membrane IBA UniProtKB:Q13635, FB:FBgn0003892, PANTHER:PTN002916954, MGI:MGI:105373 Gaudet et al., 2010
Biological Process camera-type eye development IMP MO1-ptch2 Lee et al., 2008
camera-type eye development IMP ptch2tc294z/tc294z 2 Publications
cardioblast differentiation IGI ptch1tj222/tj222; ptch2hu1602/hu1602 Thomas et al., 2008
negative regulation of muscle organ development IGI hhip Ochi et al., 2006
negative regulation of muscle organ development IGI MO1-ptch1, MO3-hhip, MO2-hhip Ochi et al., 2006
negative regulation of smoothened signaling pathway IMP ptch2au1/au1 Lee et al., 2012
osteoblast differentiation IMP ptch2hu1602/hu1602 Hammond et al., 2009
proximal/distal pattern formation IMP MO1-ptch2 Lee et al., 2008
proximal/distal pattern formation IMP ptch2tc294z/tc294z Lee et al., 2008
retinal ganglion cell axon guidance IMP ptch2tc294z/tc294z Karlstrom et al., 1996
smoothened signaling pathway IBA UniProtKB:Q13635, PANTHER:PTN000847539, MGI:MGI:105373 Gaudet et al., 2010
smoothened signaling pathway IMP MO1-ptch2 Wilson et al., 2009