ZFIN ID: ZDB-GENE-980526-41
Gene Name: sonic hedgehog signaling molecule b
Gene Symbol: shhb
GO Details
Ontology Qualifier Term Evidence Inferred From Annotation Extension Reference(s)
Molecular Function calcium ion binding IBA UniProtKB:O43323, PANTHER:PTN001726121, UniProtKB:Q15465, UniProtKB:Q14623 Gaudet et al., 2010
hydrolase activity IEA UniProtKB-KW:KW-0378 ZFIN Electronic Annotation
metal ion binding IEA UniProtKB-KW:KW-0479 ZFIN Electronic Annotation
patched binding IBA MGI:MGI:94891, PANTHER:PTN001726121, MGI:MGI:98297, UniProtKB:Q15465, UniProtKB:Q14623, MGI:MGI:96533 Gaudet et al., 2010
peptidase activity IEA InterPro:IPR001767 ZFIN Electronic Annotation
peptidase activity IEA UniProtKB-KW:KW-0645 ZFIN Electronic Annotation
Cellular Component extracellular region IEA UniProtKB-KW:KW-0964 ZFIN Electronic Annotation
extracellular space IBA PANTHER:PTN001726121, MGI:MGI:98297, UniProtKB:Q91035, RGD:3673, UniProtKB:Q15465, UniProtKB:Q98938, UniProtKB:F1P3J4, FB:FBgn0004644 Gaudet et al., 2010
membrane IEA UniProtKB-KW:KW-0472 ZFIN Electronic Annotation
plasma membrane IEA UniProtKB-KW:KW-1003 ZFIN Electronic Annotation
plasma membrane IEA UniProtKB-SubCell:SL-0039 UniProt-GOA
Biological Process cell fate specification IBA PANTHER:PTN001726121, MGI:MGI:98297, RGD:3673, MGI:MGI:96533 Gaudet et al., 2010
cell-cell signaling IEA InterPro:IPR000320 ZFIN Electronic Annotation
cell-cell signaling IEA InterPro:IPR001657 ZFIN Electronic Annotation
embryonic neurocranium morphogenesis IGI MO1-shha, MO2-shhb Wada et al., 2005
embryonic viscerocranium morphogenesis IGI MO1-shha, MO2-shhb Eberhart et al., 2006
endocardial cell differentiation IGI MO1-shha, MO1-shhb Wong et al., 2012
forebrain development IMP MO3-shhb Scholpp et al., 2006
gliogenesis IGI shhaDf(Chr07)t4/t4 Park et al., 2004
multicellular organism development IEA InterPro:IPR001657 ZFIN Electronic Annotation
multicellular organism development IEA UniProtKB-KW:KW-0217 ZFIN Electronic Annotation
neuron differentiation IMP Takamiya et al., 2006
neuron fate commitment IGI shhaDf(Chr07)t4/t4 Park et al., 2004
oligodendrocyte differentiation IBA PANTHER:PTN002484206 Gaudet et al., 2010
proteolysis IEA InterPro:IPR001767 ZFIN Electronic Annotation
proteolysis IEA UniProtKB-KW:KW-0645 ZFIN Electronic Annotation
regulation of gene expression IBA PANTHER:PTN001726121, MGI:MGI:98297, UniProtKB:Q91035, UniProtKB:Q15465, UniProtKB:Q98938, UniProtKB:F1P3J4, MGI:MGI:96533 Gaudet et al., 2010
smoothened signaling pathway IBA PANTHER:PTN001726121, MGI:MGI:94891, MGI:MGI:98297, UniProtKB:Q15465, UniProtKB:Q14623, UniProtKB:Q98938, FB:FBgn0004644, MGI:MGI:96533 Gaudet et al., 2010
striated muscle cell development IGI gli2aty119/ty119 Du et al., 2001