ZFIN ID: ZDB-GENE-980526-268
Gene Name: GATA binding protein 1a
Gene Symbol: gata1a
GO Details
Ontology Qualifier Term Evidence Inferred From Annotation Extension Reference(s)
Molecular Function DNA-binding transcription factor activity IDA 2 Publications
DNA-binding transcription factor activity IEA InterPro:IPR039355 ZFIN Electronic Annotation
DNA-binding transcription factor activity, RNA polymerase II-specific IBA UniProtKB:Q92908, SGD:S000003646, UniProtKB:P23771, SGD:S000001742, SGD:S000001873, RGD:2665, WB:WBGene00001250, FB:FBgn0003507, UniProtKB:P43694, MGI:MGI:107516, PomBase:SPAC23E2.01, PomBase:SPCC1393.08, PomBase:SPCC1902.01, MGI:MGI:95663, MGI:MGI:95662, FB:FBgn0003117, MGI:MGI:95664, UniProtKB:P15976, MGI:MGI:95661, UniProtKB:P23769, MGI:MGI:109497, WB:WBGene00001249, PANTHER:PTN001600628 Gaudet et al., 2010
double-stranded DNA binding IDA Lyons et al., 2002
metal ion binding IEA UniProtKB-KW:KW-0479 ZFIN Electronic Annotation
protein binding IPI foxo3b Hu et al., 2014
RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA UniProtKB:P23771, MGI:MGI:95661, SGD:S000000842, MGI:MGI:107516, PomBase:SPAC23E2.01, PomBase:SPCC1902.01, MGI:MGI:95663, MGI:MGI:95662, PANTHER:PTN001600628, MGI:MGI:95664, UniProtKB:P15976 Gaudet et al., 2010
sequence-specific DNA binding IDA Belele et al., 2009
sequence-specific DNA binding IEA InterPro:IPR000679 ZFIN Electronic Annotation
zinc ion binding IEA InterPro:IPR000679 ZFIN Electronic Annotation
zinc ion binding IEA InterPro:IPR013088 ZFIN Electronic Annotation
zinc ion binding IEA InterPro:IPR039355 ZFIN Electronic Annotation
Cellular Component nucleus IC DNA-binding transcription factor activity Lyons et al., 2002
nucleus IBA UniProtKB:Q92908, SGD:S000003646, SGD:S000001742, UniProtKB:E1C9C6, UniProtKB:P43691, WB:WBGene00001250, UniProtKB:P43692, WB:WBGene00001251, WB:WBGene00001252, UniProtKB:P43694, WB:WBGene00001253, PomBase:SPAC23E2.01, UniProtKB:I3LUZ9, FB:FBgn0003117, UniProtKB:P15976, MGI:MGI:95661, RGD:621250, UniProtKB:F1NZV5, UniProtKB:P23769, WB:WBGene00001311, FB:FBgn0032223, PANTHER:PTN001600628, RGD:2664, UniProtKB:P23771, RGD:2663, SGD:S000001873, RGD:2666, RGD:2665, WB:WBGene00001186, SGD:S000000842, MGI:MGI:107516, PomBase:SPCC1902.01, MGI:MGI:95663, MGI:MGI:95662, UniProtKB:Q9BWX5, FB:FBgn0038391, MGI:MGI:95664, WB:WBGene00015981, MGI:MGI:109497, WB:WBGene00001249 Gaudet et al., 2010
nucleus IEA UniProtKB-KW:KW-0539 ZFIN Electronic Annotation
Biological Process cardiac muscle tissue development IBA PANTHER:PTN002560190, RGD:2665, MGI:MGI:95664 Gaudet et al., 2010
cell fate commitment IBA WB:WBGene00001186, UniProtKB:P23769, PANTHER:PTN000800998, MGI:MGI:95663, MGI:MGI:95662, UniProtKB:P15976, MGI:MGI:95664 Gaudet et al., 2010
chordate embryonic development IMP trim33unspecified Traver et al., 2003
NOT definitive hemopoiesis IMP gata1am651/m651 Belele et al., 2009
NOT definitive hemopoiesis IMP gata1ahg2/+; gata1am651/+ Belele et al., 2009
embryonic hemopoiesis IMP gata1am651/m651 Lyons et al., 2002
erythrocyte development IMP MO1-gata1a Vermot et al., 2009
erythrocyte differentiation IMP MO1-gata1a Woo et al., 2008
erythrocyte differentiation IMP gata1am651/m651 (AB) Traver et al., 2003
macrophage differentiation IMP gata1am651/m651 Belele et al., 2009
macrophage differentiation IMP gata1ahg2/+; gata1am651/+ Belele et al., 2009
monocyte differentiation IMP gata1am651/m651 Belele et al., 2009
monocyte differentiation IMP gata1ahg2/+; gata1am651/+ Belele et al., 2009
myeloid cell differentiation IGI MO1-gata1a, MO1-klf17 Kitaguchi et al., 2009
myeloid cell differentiation IGI gata1am651/m651 , MO1-klf17 Kitaguchi et al., 2009
negative regulation of apoptotic process IMP gata1am651/m651 (AB) Galloway et al., 2005
negative regulation of gene expression IGI MO1-gata1a, MO1-klf17 Kitaguchi et al., 2009
negative regulation of gene expression IGI gata1am651/m651 , MO1-klf17 Kitaguchi et al., 2009
negative regulation of gene expression IMP gata1am651/m651 Kitaguchi et al., 2009
neutrophil differentiation IMP MO1-gata1a Glenn et al., 2014
positive regulation of transcription by RNA polymerase II IMP Kobayashi et al., 2001
primitive hemopoiesis IGI MO1-gata2a, gata1am651/m651 Belele et al., 2009
primitive hemopoiesis IMP gata1am651/m651 Belele et al., 2009
primitive hemopoiesis IMP gata1ahg2/+; gata1am651/+ Belele et al., 2009
primitive hemopoiesis IMP gata1am651/m651 (AB) Weinstein et al., 1996
regulation of myeloid cell differentiation IMP MO1-gata1a 2 Publications
regulation of myeloid cell differentiation IMP gata1am651/m651 (AB) Rhodes et al., 2005
regulation of transcription, DNA-templated IEA InterPro:IPR000679 ZFIN Electronic Annotation
regulation of transcription, DNA-templated IEA InterPro:IPR013088 ZFIN Electronic Annotation