ZFIN ID: ZDB-GENE-110411-139
Gene Name: sclerostin
Gene Symbol: sost
GO Details
Ontology Qualifier Term Evidence Inferred From Annotation Extension Reference(s)
Molecular Function BMP binding IBA UniProtKB:Q6X4U4, PANTHER:PTN001028853 Gaudet et al., 2010
heparin binding IEA UniProtKB-KW:KW-0358 ZFIN Electronic Annotation
Cellular Component extracellular space IBA MGI:MGI:1913292, UniProtKB:Q6X4U4, PANTHER:PTN001028853, RGD:69358 Gaudet et al., 2010
extracellular space IEA InterPro:IPR008835 ZFIN Electronic Annotation
Biological Process negative regulation of BMP signaling pathway IBA MGI:MGI:1921749, MGI:MGI:1913292, UniProtKB:Q6X4U4, PANTHER:PTN001028853, UniProtKB:Q9BQB4 Gaudet et al., 2010
negative regulation of ossification IEA InterPro:IPR015665 ZFIN Electronic Annotation
negative regulation of Wnt signaling pathway IBA MGI:MGI:1921749, MGI:MGI:1913292, UniProtKB:Q6X4U4, PANTHER:PTN001028853, UniProtKB:Q9BQB4 Gaudet et al., 2010
ossification IBA MGI:MGI:1921749, RGD:69358, PANTHER:PTN002686518 Gaudet et al., 2010