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General Information
ZIRC
ZFIN ID: ZDB-GENE-091118-1
Gene Name: colony stimulating factor 1 receptor, b
Gene Symbol: csf1rb
GO Details
Ontology Qualifier Term Evidence Inferred From Annotation Extension Reference(s)
Molecular Function ATP binding IEA InterPro:IPR000719 ZFIN Electronic Annotation
ATP binding IEA InterPro:IPR001824 ZFIN Electronic Annotation
ATP binding IEA InterPro:IPR017441 ZFIN Electronic Annotation
ATP binding IEA UniProtKB-KW:KW-0067 ZFIN Electronic Annotation
cytokine binding IEA InterPro:IPR030658 ZFIN Electronic Annotation
growth factor binding IBA MGI:MGI:97530, UniProtKB:P09619, UniProtKB:P16234, PANTHER:PTN001974966 Gaudet et al., 2010
kinase activity IEA UniProtKB-KW:KW-0418 ZFIN Electronic Annotation
macrophage colony-stimulating factor receptor activity IBA PANTHER:PTN002814394, UniProtKB:P07333, MGI:MGI:1339758 Gaudet et al., 2010
nucleotide binding IEA UniProtKB-KW:KW-0547 ZFIN Electronic Annotation
protein kinase activity IEA InterPro:IPR000719 ZFIN Electronic Annotation
protein kinase activity IEA InterPro:IPR001245 ZFIN Electronic Annotation
protein kinase activity IEA InterPro:IPR008266 ZFIN Electronic Annotation
protein tyrosine kinase activity IEA InterPro:IPR020635 ZFIN Electronic Annotation
protein tyrosine kinase activity IEA UniProtKB-KW:KW-0829 ZFIN Electronic Annotation
transferase activity IEA UniProtKB-KW:KW-0808 ZFIN Electronic Annotation
transmembrane receptor protein tyrosine kinase activity IBA UniProtKB:P04626, RGD:2611, MGI:MGI:96969, UniProtKB:P04629, RGD:621737, UniProtKB:P54762, UniProtKB:P29320, MGI:MGI:95558, FB:FBgn0003733, UniProtKB:P35968, FB:FBgn0003731, UniProtKB:P17948, MGI:MGI:95561, MGI:MGI:98277, UniProtKB:P08069, MGI:MGI:97384, UniProtKB:P07333, UniProtKB:P54760, UniProtKB:P22455, UniProtKB:P21802, UniProtKB:Q08345, RGD:2543, MGI:MGI:109378, RGD:2621, UniProtKB:P54753, MGI:MGI:1345277, RGD:620714, UniProtKB:P14616, MGI:MGI:1339758, FB:FBgn0285896, MGI:MGI:96677, MGI:MGI:97530, FB:FBgn0003366, MGI:MGI:95276, MGI:MGI:96683, UniProtKB:P16234, PANTHER:PTN002356460, RGD:2869, RGD:620831, WB:WBGene00020504, UniProtKB:P00533, UniProtKB:P09619, FB:FBgn0040505, RGD:3285, RGD:3284, MGI:MGI:99612, RGD:3082, MGI:MGI:99611, UniProtKB:P10721, WB:WBGene00000289, RGD:2917, UniProtKB:P21709, WB:WBGene00006868, UniProtKB:Q16832, UniProtKB:Q91987, FB:FBgn0032006, UniProtKB:Q15303, RGD:620144, RGD:3214, UniProtKB:P29317, RGD:3213, UniProtKB:P07949, UniProtKB:P35916, MGI:MGI:95524, MGI:MGI:97902, UniProtKB:Q5JZY3, FB:FBgn0283499, MGI:MGI:95522, MGI:MGI:99654, UniProtKB:P22607, UniProtKB:P11362, MGI:MGI:95294, UniProtKB:Q9UM73, UniProtKB:P06213, RGD:2965, UniProtKB:Q16620, FB:FBgn0010389 Gaudet et al., 2010
transmembrane receptor protein tyrosine kinase activity IBA RGD:2611, UniProtKB:P04626, MGI:MGI:96969, UniProtKB:P04629, RGD:621737, UniProtKB:P54762, UniProtKB:P29320, MGI:MGI:95558, FB:FBgn0003733, UniProtKB:P35968, FB:FBgn0003731, MGI:MGI:98277, MGI:MGI:95561, UniProtKB:P17948, MGI:MGI:97384, UniProtKB:P08069, UniProtKB:P07333, UniProtKB:P54760, UniProtKB:P22455, UniProtKB:P21802, RGD:2543, UniProtKB:Q08345, MGI:MGI:109378, RGD:2621, MGI:MGI:1345277, UniProtKB:P54753, RGD:620714, UniProtKB:P14616, FB:FBgn0285896, MGI:MGI:1339758, MGI:MGI:96677, MGI:MGI:97530, FB:FBgn0003366, MGI:MGI:95276, MGI:MGI:96683, UniProtKB:P16234, PANTHER:PTN002356460, RGD:2869, RGD:620831, WB:WBGene00020504, UniProtKB:P00533, UniProtKB:P09619, FB:FBgn0040505, RGD:3285, RGD:3284, MGI:MGI:99612, RGD:3082, MGI:MGI:99611, UniProtKB:P10721, RGD:2917, WB:WBGene00000289, UniProtKB:P21709, WB:WBGene00006868, UniProtKB:Q91987, UniProtKB:Q16832, FB:FBgn0032006, UniProtKB:Q15303, RGD:620144, UniProtKB:P29317, RGD:3214, RGD:3213, UniProtKB:P07949, UniProtKB:P35916, MGI:MGI:95524, MGI:MGI:97902, UniProtKB:Q5JZY3, MGI:MGI:95522, FB:FBgn0283499, MGI:MGI:99654, UniProtKB:P22607, UniProtKB:P11362, MGI:MGI:95294, UniProtKB:Q9UM73, UniProtKB:P06213, RGD:2965, UniProtKB:Q16620, FB:FBgn0010389 Gaudet et al., 2010
transmembrane receptor protein tyrosine kinase activity IEA InterPro:IPR001824 ZFIN Electronic Annotation
transmembrane receptor protein tyrosine kinase activity IEA InterPro:IPR030658 ZFIN Electronic Annotation
Cellular Component CSF1-CSF1R complex IBA PANTHER:PTN002814394, MGI:MGI:1339758 Gaudet et al., 2010
integral component of membrane IEA UniProtKB-KW:KW-0812 ZFIN Electronic Annotation
integral component of plasma membrane IBA MGI:MGI:104771, UniProtKB:P04629, UniProtKB:P54762, UniProtKB:P29320, RGD:70957, FB:FBgn0015380, FB:FBgn0003733, UniProtKB:P35968, FB:FBgn0003731, MGI:MGI:99611, MGI:MGI:98277, UniProtKB:P17948, FB:FBgn0011829, WB:WBGene00000289, UniProtKB:P21709, UniProtKB:P54760, UniProtKB:P22455, UniProtKB:P21802, FB:FBgn0032006, MGI:MGI:103581, UniProtKB:P29317, RGD:3214, RGD:3213, UniProtKB:P07949, MGI:MGI:109378, UniProtKB:P54753, RGD:1560587, UniProtKB:Q02763, FB:FBgn0283499, WB:WBGene00000898, FB:FBgn0003366, UniProtKB:P22607, UniProtKB:P16234, PANTHER:PTN002356460, UniProtKB:Q9UM73, UniProtKB:P06213, UniProtKB:Q16620 Gaudet et al., 2010
integral component of plasma membrane IBA MGI:MGI:104771, UniProtKB:P04629, UniProtKB:P54762, UniProtKB:P29320, RGD:70957, FB:FBgn0015380, FB:FBgn0003733, UniProtKB:P35968, MGI:MGI:99611, FB:FBgn0003731, MGI:MGI:98277, UniProtKB:P17948, FB:FBgn0011829, WB:WBGene00000289, UniProtKB:P21709, UniProtKB:P54760, UniProtKB:P22455, UniProtKB:P21802, FB:FBgn0032006, MGI:MGI:103581, RGD:3214, UniProtKB:P29317, RGD:3213, UniProtKB:P07949, MGI:MGI:109378, UniProtKB:P54753, RGD:1560587, UniProtKB:Q02763, FB:FBgn0283499, FB:FBgn0003366, WB:WBGene00000898, UniProtKB:P22607, UniProtKB:P16234, PANTHER:PTN002356460, UniProtKB:Q9UM73, UniProtKB:P06213, UniProtKB:Q16620 Gaudet et al., 2010
membrane IEA UniProtKB-KW:KW-0472 ZFIN Electronic Annotation
receptor complex IBA UniProtKB:Q08345, UniProtKB:P04626, UniProtKB:P07949, UniProtKB:P35916, UniProtKB:P21860, UniProtKB:P04629, FB:FBgn0033791, UniProtKB:O15146, UniProtKB:A6QR62, UniProtKB:P14616, FB:FBgn0024245, FB:FBgn0015380, UniProtKB:Q01973, UniProtKB:P17948, UniProtKB:P08069, PANTHER:PTN002356460, UniProtKB:P11362, UniProtKB:P06213, UniProtKB:Q16288, UniProtKB:Q15303, UniProtKB:Q16620, UniProtKB:P00533 Gaudet et al., 2010
receptor complex IBA UniProtKB:Q08345, UniProtKB:P07949, UniProtKB:P04626, UniProtKB:P35916, UniProtKB:P21860, UniProtKB:P04629, UniProtKB:O15146, FB:FBgn0033791, UniProtKB:A6QR62, UniProtKB:P14616, FB:FBgn0024245, UniProtKB:Q01973, FB:FBgn0015380, UniProtKB:P17948, UniProtKB:P08069, UniProtKB:P11362, PANTHER:PTN002356460, UniProtKB:P06213, UniProtKB:Q16288, UniProtKB:Q15303, UniProtKB:Q16620, UniProtKB:P00533 Gaudet et al., 2010
Biological Process cytokine-mediated signaling pathway IEA InterPro:IPR030658 ZFIN Electronic Annotation
hematopoietic progenitor cell differentiation IBA MGI:MGI:97530, UniProtKB:A0A0G2L2B8, PANTHER:PTN001230732, MGI:MGI:95559, MGI:MGI:96677 Gaudet et al., 2010
multicellular organism development IBA PANTHER:PTN002356460, MGI:MGI:1346037, MGI:MGI:95523, MGI:MGI:95559, MGI:MGI:96433, MGI:MGI:96575, FB:FBgn0003733, MGI:MGI:99216 Gaudet et al., 2010
multicellular organism development IBA MGI:MGI:1346037, PANTHER:PTN002356460, MGI:MGI:95523, MGI:MGI:95559, MGI:MGI:96433, MGI:MGI:96575, FB:FBgn0003733, MGI:MGI:99216 Gaudet et al., 2010
osteoclast differentiation IBA PANTHER:PTN002814394, MGI:MGI:1339758 Gaudet et al., 2010
phosphorylation IEA UniProtKB-KW:KW-0418 ZFIN Electronic Annotation
positive regulation of kinase activity IBA PANTHER:PTN002356460, UniProtKB:Q16832 Gaudet et al., 2010
protein phosphorylation IEA InterPro:IPR000719 ZFIN Electronic Annotation
protein phosphorylation IEA InterPro:IPR001245 ZFIN Electronic Annotation
protein phosphorylation IEA InterPro:IPR001824 ZFIN Electronic Annotation
protein phosphorylation IEA InterPro:IPR008266 ZFIN Electronic Annotation
protein phosphorylation IEA InterPro:IPR020635 ZFIN Electronic Annotation
transmembrane receptor protein tyrosine kinase signaling pathway IBA UniProtKB:P04626, RGD:2611, MGI:MGI:96969, UniProtKB:P04629, UniProtKB:P54764, RGD:621737, UniProtKB:P54762, UniProtKB:P29320, MGI:MGI:104757, MGI:MGI:95558, MGI:MGI:95278, FB:FBgn0003733, UniProtKB:P35968, FB:FBgn0003731, MGI:MGI:98277, MGI:MGI:95561, UniProtKB:P17948, RGD:69323, UniProtKB:P08069, MGI:MGI:97384, UniProtKB:P54760, UniProtKB:P22455, UniProtKB:P21802, RGD:2612, UniProtKB:Q08345, RGD:2543, MGI:MGI:109378, RGD:2621, MGI:MGI:1345277, UniProtKB:P54753, RGD:620714, UniProtKB:Q02763, FB:FBgn0285896, MGI:MGI:1339758, MGI:MGI:96677, MGI:MGI:97530, MGI:MGI:97531, FB:FBgn0003366, MGI:MGI:95276, MGI:MGI:96683, UniProtKB:P16234, PANTHER:PTN002356460, RGD:2869, RGD:620831, UniProtKB:Q16288, UniProtKB:P00533, MGI:MGI:1096337, UniProtKB:P09619, UniProtKB:A6QR62, RGD:3285, RGD:3284, MGI:MGI:99612, MGI:MGI:99216, MGI:MGI:99611, RGD:3082, UniProtKB:P10721, RGD:2917, UniProtKB:P21709, WB:WBGene00006868, UniProtKB:Q16832, UniProtKB:Q91987, UniProtKB:Q15303, FB:FBgn0032006, RGD:620144, RGD:3214, UniProtKB:P29317, RGD:3213, UniProtKB:P07949, WB:WBGene00001184, UniProtKB:P35916, MGI:MGI:95524, MGI:MGI:95523, MGI:MGI:97902, MGI:MGI:95525, UniProtKB:Q5JZY3, MGI:MGI:96575, MGI:MGI:95522, FB:FBgn0283499, MGI:MGI:99654, UniProtKB:P22607, UniProtKB:P11362, MGI:MGI:95294, UniProtKB:Q15375, UniProtKB:P06213, RGD:2965, UniProtKB:Q16620, FB:FBgn0010389 Gaudet et al., 2010
transmembrane receptor protein tyrosine kinase signaling pathway IBA RGD:2611, UniProtKB:P04626, MGI:MGI:96969, UniProtKB:P54764, UniProtKB:P04629, RGD:621737, UniProtKB:P54762, UniProtKB:P29320, MGI:MGI:104757, MGI:MGI:95558, MGI:MGI:95278, FB:FBgn0003733, UniProtKB:P35968, FB:FBgn0003731, MGI:MGI:98277, MGI:MGI:95561, UniProtKB:P17948, UniProtKB:P08069, RGD:69323, MGI:MGI:97384, UniProtKB:P54760, UniProtKB:P22455, UniProtKB:P21802, RGD:2612, UniProtKB:Q08345, RGD:2543, MGI:MGI:109378, RGD:2621, UniProtKB:P54753, MGI:MGI:1345277, RGD:620714, UniProtKB:Q02763, FB:FBgn0285896, MGI:MGI:1339758, MGI:MGI:96677, MGI:MGI:97530, MGI:MGI:97531, FB:FBgn0003366, MGI:MGI:95276, MGI:MGI:96683, UniProtKB:P16234, PANTHER:PTN002356460, RGD:2869, RGD:620831, UniProtKB:Q16288, UniProtKB:P00533, MGI:MGI:1096337, UniProtKB:P09619, UniProtKB:A6QR62, RGD:3285, RGD:3284, MGI:MGI:99612, MGI:MGI:99216, UniProtKB:P10721, RGD:3082, MGI:MGI:99611, RGD:2917, UniProtKB:P21709, UniProtKB:Q91987, UniProtKB:Q16832, WB:WBGene00006868, UniProtKB:Q15303, FB:FBgn0032006, RGD:620144, RGD:3214, UniProtKB:P29317, RGD:3213, UniProtKB:P07949, WB:WBGene00001184, UniProtKB:P35916, MGI:MGI:95524, MGI:MGI:97902, MGI:MGI:95523, MGI:MGI:95525, UniProtKB:Q5JZY3, MGI:MGI:96575, MGI:MGI:95522, FB:FBgn0283499, MGI:MGI:99654, UniProtKB:P22607, UniProtKB:P11362, MGI:MGI:95294, UniProtKB:Q15375, UniProtKB:P06213, RGD:2965, UniProtKB:Q16620, FB:FBgn0010389 Gaudet et al., 2010
transmembrane receptor protein tyrosine kinase signaling pathway IEA InterPro:IPR001824 ZFIN Electronic Annotation