Gene
cacna1g
- ID
- ZDB-GENE-090514-2
- Name
- calcium channel, voltage-dependent, T type, alpha 1G subunit
- Symbol
- cacna1g Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 12 Mapping Details/Browsers
- Description
- Predicted to have low voltage-gated calcium channel activity and voltage-gated sodium channel activity. Predicted to be involved in several processes, including calcium ion import; neuronal action potential; and positive regulation of calcium ion-dependent exocytosis. Predicted to localize to neuron projection and voltage-gated sodium channel complex. Human ortholog(s) of this gene implicated in cerebellar ataxia type 42. Is expressed in atrium and cardiac ventricle. Orthologous to human CACNA1G (calcium voltage-gated channel subunit alpha1 G).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 3 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| cerebellar ataxia type 42 | Alliance | Spinocerebellar ataxia 42 | 616795 |
| Spinocerebellar ataxia 42, early-onset, severe, with neurodevelopmental deficits | 618087 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR005821 | Ion transport domain |
| Family | IPR002077 | Voltage-dependent calcium channel, alpha-1 subunit |
| Family | IPR005445 | Voltage-dependent calcium channel, T-type, alpha-1 subunit |
| Family | IPR043203 | Voltage-gated cation channel calcium and sodium |
| Homologous_superfamily | IPR027359 | Voltage-dependent channel domain superfamily |
Domain Details Per Protein
| Protein | Length | Ion transport domain | Voltage-dependent calcium channel, alpha-1 subunit | Voltage-dependent calcium channel, T-type, alpha-1 subunit | Voltage-dependent channel domain superfamily | Voltage-gated cation channel calcium and sodium |
|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M9QER5
|
2414 | |||||
|
UniProtKB:A0A8M9QJ76
|
2462 | |||||
|
UniProtKB:A0A8M6Z8Y9
|
2456 | |||||
|
UniProtKB:A0A8M6Z3L0
|
2469 | |||||
|
UniProtKB:A0A8M6Z219
|
2447 | |||||
|
UniProtKB:A0A8M9PX46
|
2462 | |||||
|
UniProtKB:A0A8M9QER1
|
2503 | |||||
|
UniProtKB:A0A8M9QMZ6
|
2478 | |||||
|
UniProtKB:A0A8M9Q929
|
2440 |
| Type | Name | Annotation Method | Length (nt) | Analysis |
|---|---|---|---|---|
| mRNA |
cacna1g-202
(1)
|
Havana | 5635 nt |
Interactions and Pathways
No data available
Plasmids
No data available