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General Information
ZIRC
ZFIN ID: ZDB-GENE-090313-71
Gene Name: DNA replication helicase/nuclease 2
Gene Symbol: dna2
GO Details
Ontology Qualifier Term Evidence Inferred From Annotation Extension Reference(s)
Molecular Function 5'-flap endonuclease activity IBA SGD:S000001207, UniProtKB:P51530, MGI:MGI:2443732, PANTHER:PTN000094675 Gaudet et al., 2010
5'-flap endonuclease activity IEA InterPro:IPR026851 ZFIN Electronic Annotation
5'-flap endonuclease activity ISS UniProtKB:P51530 GOA et al., 2007
RNA binding IBA PANTHER:PTN000094509, UniProtKB:Q9HCE1, UniProtKB:Q92900, TAIR:locus:2064158, TAIR:locus:2171007 Gaudet et al., 2010
single-stranded DNA helicase activity IEA InterPro:IPR026851 ZFIN Electronic Annotation
site-specific endodeoxyribonuclease activity, specific for altered base ISS UniProtKB:P51530 GOA et al., 2007
Cellular Component cytoplasm IBA SGD:S000001207, UniProtKB:P51530, PomBase:SPBC16D10.04c, PANTHER:PTN000094675 Gaudet et al., 2010
COLOCALIZES WITH gamma DNA polymerase complex ISS UniProtKB:P51530 GOA et al., 2007
nuclear chromosome, telomeric region IBA SGD:S000001207, MGI:MGI:2443732, PomBase:SPBC16D10.04c, PANTHER:PTN000094675 Gaudet et al., 2010
nucleus IBA SGD:S000001207, UniProtKB:P51530, UniProtKB:A0A1P8ASY1, WB:WBGene00001016, PANTHER:PTN000094675 Gaudet et al., 2010
Biological Process base-excision repair ISS UniProtKB:P51530 GOA et al., 2007
DNA metabolic process ISS UniProtKB:P51530 GOA et al., 2007
DNA replication, Okazaki fragment processing IEA InterPro:IPR026851 ZFIN Electronic Annotation
DNA replication, removal of RNA primer ISS UniProtKB:P51530 GOA et al., 2007
mitochondrial DNA replication ISS UniProtKB:P51530 GOA et al., 2007
nucleic acid phosphodiester bond hydrolysis ISS UniProtKB:P51530 GOA et al., 2007
positive regulation of DNA replication ISS UniProtKB:P51530 GOA et al., 2007
replication fork reversal IBA PomBase:SPBC16D10.04c, PANTHER:PTN000094675 Gaudet et al., 2010