Gene

wnk3

ID
ZDB-GENE-090312-81
Name
WNK lysine deficient protein kinase 3
Symbol
wnk3 Nomenclature History
Previous Names
  • wnk3l (1)
  • im:7152756
  • si:dkey-151g10.3 (1)
  • wnk3-like (1)
Type
protein_coding_gene
Location
Chr: 23 Mapping Details/Browsers
Description
Predicted to have chloride channel inhibitor activity; potassium channel inhibitor activity; and protein serine/threonine kinase activity. Predicted to be involved in several processes, including intracellular signal transduction; protein phosphorylation; and regulation of metal ion transport. Predicted to localize to cytosol.
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Thisse et al., 2004
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With wnk3 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Prieto syndrome Alliance Prieto syndrome 309610
Associated With wnk3 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Active_site IPR008271 Serine/threonine-protein kinase, active site
Domain IPR000719 Protein kinase domain
Domain IPR024678 Serine/threonine-protein kinase OSR1/WNK, CCT domain
Homologous_superfamily IPR011009 Protein kinase-like domain superfamily
Domain Details Per Protein
Protein Length Protein kinase domain Protein kinase-like domain superfamily Serine/threonine-protein kinase, active site Serine/threonine-protein kinase OSR1/WNK, CCT domain
UniProtKB:A0A8M9PFG8 2994
UniProtKB:A0A8M3B680 2693
UniProtKB:A0A8M9PTI7 3056
UniProtKB:A0A8M3AVG7 3053
UniProtKB:A0A8M9PWV5 1953
UniProtKB:A0A8M9PL63 2696
UniProtKB:A0A8N7TFG0 3006
UniProtKB:A0A8M3ANR2 1950
UniProtKB:A0A8M9P5H4 3009
UniProtKB:A0A8M3AN04 2991
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations