Gene
kcnma1a
- ID
- ZDB-GENE-070202-9
- Name
- potassium large conductance calcium-activated channel, subfamily M, alpha member 1a
- Symbol
- kcnma1a Nomenclature History
- Previous Names
-
- kcnma1
- slo1a (1)
- si:ch211-39f22.2
- Type
- protein_coding_gene
- Location
- Chr: 13 Mapping Details/Browsers
- Description
- Predicted to have large conductance calcium-activated potassium channel activity. Involved in response to auditory stimulus. Predicted to localize to postsynaptic membrane. Human ortholog(s) of this gene implicated in Alzheimer's disease and idiopathic generalized epilepsy. Is expressed in otic vesicle. Orthologous to human KCNMA1 (potassium calcium-activated channel subfamily M alpha 1).
- Genome Resources
- Note
- None
- Comparative Information
- All Expression Data
- 4 figures from 4 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 2 figures from Rohmann et al., 2014
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
---|---|---|---|
paroxysmal nonkinesigenic dyskinesia 3 | Alliance | Paroxysmal nonkinesigenic dyskinesia, 3, with or without generalized epilepsy | 609446 |
Cerebellar atrophy, developmental delay, and seizures | 617643 | ||
Liang-Wang syndrome | 618729 | ||
{Epilepsy, idiopathic generalized, susceptibility to, 16} | 618596 |
Domain, Family, and Site Summary
Domain Details Per Protein
Type | Name | Length (nt) | Analysis |
---|---|---|---|
mRNA |
kcnma1a-205
(1)
|
3823 nt | |
ncRNA |
kcnma1a-002
(1)
|
849 nt | |
ncRNA |
kcnma1a-003
(1)
|
725 nt | |
ncRNA |
kcnma1a-004
(1)
|
857 nt |
Interactions and Pathways
No data available
Plasmids